Osteoarticular manifestations of human brucellosis: A review

World Journal of Orthopedics
Seyed Mokhtar Esmaeilnejad-Ganji, Seyed Mohammad Reza Esmaeilnejad-Ganji

Abstract

Brucellosis is a common global zoonotic disease, which is responsible for a range of clinical manifestations. Fever, sweating and musculoskeletal pains are observed in most patients. The most frequent complication of brucellosis is osteoarticular involvement, with 10% to 85% of patients affected. The sacroiliac (up to 80%) and spinal joints (up to 54%) are the most common affected sites. Spondylitis and spondylodiscitis are the most frequent complications of brucellar spinal involvement. Peripheral arthritis, osteomyelitis, discitis, bursitis and tenosynovitis are other osteoarticular manifestations, but with a lower prevalence. Spinal brucellosis has two forms: focal and diffuse. Epidural abscess is a rare complication of spinal brucellosis but can lead to permanent neurological deficits or even death if not treated promptly. Spondylodiscitis is the most severe form of osteoarticular involvement by brucellosis, and can have single- or multi-focal involvement. Early and appropriate diagnosis and treatment of the disease is important in order to have a successful management of the patients with osteoarticular brucellosis. Brucellosis should be considered as a differential diagnosis for sciatic and back pain, especially in endemi...Continue Reading

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Citations

Aug 10, 2019·Case Reports in Infectious Diseases·Abdullah BalkhairHashim Ba Taher
Jul 14, 2020·Clinical Rheumatology·Mustafa ÇakanNuray Aktay Ayaz
Mar 19, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Na WuYong-Sheng Yu
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Jan 26, 2021·Frontiers in Veterinary Science·Zhiguo LiuZhenjun Li
Dec 24, 2020·The Veterinary Quarterly·Sandip Kumar KhuranaWanpen Chaicumpa
Jul 14, 2021·BMJ Case Reports·Pedro Madeira MarquesJosé Augusto Barata
Sep 21, 2021·PLoS Neglected Tropical Diseases·Siwen ZhangQing Zhen

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Methods Mentioned

BETA
biopsy
imaging techniques

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