PMID: 8447510Jan 1, 1993Paper

Osteoblastoma with cartilaginous matrix. An unusual morphologic presentation in 18 cases

The American Journal of Surgical Pathology
F BertoniR A McLeod

Abstract

By definition, the occurrence of cartilaginous matrix in a bone-forming tumor eliminates the diagnosis of osteoblastoma and suggests a possible diagnosis of osteosarcoma. However, this rule is not absolute, as demonstrated by 18 cases of osteoblastoma that produced cartilaginous matrix. Hyaline cartilage was detected in four cases, and chondro-osteoid material was detected in 14 cases. In all patients, the tumor was in the appropriate patient age range and location for an osteoblastoma. The radiographic features as well as the histology, with the exception of the cartilaginous components, were in keeping with diagnosis of osteoblastoma. Intralesional excision (curettage or debulking) was performed in 13 patients and wide resection in five patients. Persistent tumor in one patient required a further intralesional excision. There were four recurrences, and no metastases were reported after follow-up of 1 to 23 years. The presence of cartilaginous matrix in a bone-forming lesion does not exclude the diagnosis of osteoblastoma and, more importantly, it is not always an indication that the tumor is an osteosarcoma.

Citations

Sep 1, 2007·Head and Neck Pathology·G Petur Nielsen, Andrew E Rosenberg
Mar 17, 2004·Annals of Diagnostic Pathology·Xinmin ZhangAndrew G Huvos
Feb 1, 1994·Human Pathology·D R LucasF H Sim
Jul 10, 2008·International Journal of Surgical Pathology·Allyson C BakerGene P Siegal
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Jan 23, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jeremy J ReynoldsDavid C Kieser
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May 20, 2006·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Kyung-Sub MoonSam-Suk Kang
Jul 1, 1996·The American Journal of Surgical Pathology·C Della Rocca, A G Huvos

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