Osteofibrous dysplasia of the tibia. Is there a need for a radical surgical approach?

The Journal of Bone and Joint Surgery. British Volume
R S LeeT W R Briggs

Abstract

Osteofibrous dysplasia is an unusual developmental condition of childhood, which almost exclusively affects the tibia. It is thought to follow a slowly progressive course and to stabilise after skeletal maturity. The possible link with adamantinoma is controversial and some authors believe that they are part of one histological process. We retrospectively reviewed 16 patients who were diagnosed as having osteofibrous dysplasia initially or on the final histological examination. Their management was diverse, depending on the severity of symptoms and the extent of the lesion. Definitive (extraperiosteal) surgery was localised "shark-bite" excision for small lesions in five patients. Extensive lesions were treated by segmental excision and fibular autograft in six patients, external fixation and bone transport in four and proximal tibial replacement in one. One patient who had a fibular autograft required further excision and bone transport for recurrence. Six initially underwent curettage and all had recurrence. There were no recurrences after localised extraperiosteal excision or bone transport. There were three confirmed cases of adamantinoma. The relevant literature is reviewed. We recommend extraperiosteal excision in all cas...Continue Reading

References

Jan 1, 1992·International Orthopaedics·N AkamatsuN A Siddiqi
Dec 1, 1993·The American Journal of Surgical Pathology·H M HazelbagP C Hogendoorn
Aug 14, 1998·Journal of Pediatric Orthopedics. Part B·T OzakiH Inoue
Jan 5, 2002·The Journal of Bone and Joint Surgery. British Volume·S KamineniA Sandison
Apr 8, 2003·Skeletal Radiology·Leonard B Kahn
Apr 1, 1995·Clinical Molecular Pathology·D C ManghamH J Mankin

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Citations

Mar 6, 2013·Head and Neck Pathology·Edward F McCarthy
Aug 12, 2008·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M NappJ R Döhler
Mar 1, 2012·Surgical Pathology Clinics·Jacquelyn A Knapik
Nov 26, 2015·International Journal of Surgery Case Reports·Ismail Hadisoebroto DilogoRangga Valentino Rawung
Nov 15, 2011·Orthopaedics & Traumatology, Surgery & Research : OTSR·M RamanoudjameP Wicart
Dec 3, 2014·European Journal of Radiology·P A TylerG Rajeswaran
Jul 15, 2016·The Indian Journal of Radiology & Imaging·Nirmal Raj GopinathanAshim Das
Oct 30, 2016·Orthopaedics & Traumatology, Surgery & Research : OTSR·S E PuchnerP T Funovics
May 22, 2018·Journal of Pediatric Orthopedics·Jong Woong ParkHan-Soo Kim
Jun 28, 2007·Yonsei Medical Journal·Soo Bong HahnHo Jung Kang
Feb 28, 2008·The American Journal of Surgical Pathology·Briana C GleasonAntonio R Perez-Atayde
Jan 30, 2007·The Journal of Bone and Joint Surgery. British Volume·R J GrimerA Abudu
Jun 2, 2009·The Journal of Bone and Joint Surgery. British Volume·B G I SpiegelbergT W R Briggs
Dec 12, 2017·Journal of Pediatric Orthopedics·Daniel WestacottAndrew Howard
Sep 6, 2007·The Journal of Bone and Joint Surgery. British Volume·H TsuchiyaK Tomita
Jun 1, 2010·The Journal of the American Academy of Orthopaedic Surgeons·Mathew J MostCarrie Y Inwards
Aug 9, 2019·Journal of Pediatric Orthopedics·Daniel WestacottAndrew Howard
Dec 29, 2010·Journal of Orthopaedic Surgery·Hiroyuki NakaharaToshifumi Ozaki
Dec 14, 2018·Rare Tumors·Shinichirou YoshidaMika Watanabe
Mar 3, 2017·The Bone & Joint Journal·D W ScholfieldL Jeys
Feb 1, 2022·The Bone & Joint Journal·Benan Dala-AliDeborah M Eastwood

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