Osteogenesis at implants without primary bone contact - an experimental study in dogs

Clinical Oral Implants Research
Stefano SivolellaDaniele Botticelli

Abstract

To evaluate the healing at implants with a moderately rough surface placed and stabilized in recipient sites of dimensions deeper and larger than that of the implants to avoid any contact between parent bone and the implant. In six Labrador dogs, premolars and first molars were extracted bilaterally in the mandible. After 3 months of healing, mucoperiosteal full-thickness flaps were elevated and the premolar area of the alveolar bony crest was selected. Three recipient sites were prepared to place three implants. One implant was used as control. The other two were placed in recipient sites which left a circumferentially and periapical prepared defect of 0.7 mm (small) and 1.2 mm (large), respectively. All implants were stabilized with passive fixation plates to maintain the implants stable and without any contact with the implant bed. After 3 months of submerged healing, the animals were sacrificed. Ground sections were prepared and analyzed histomorphometrically. The BIC% was 5.3% and 0.3% for implants placed in small and large defect sites, respectively, whereas it was 46.1% for control implants. The differences were statistically significant. The width of the residual defects was 0.4 and 0.5 mm at the small and large defects...Continue Reading

References

Jun 1, 1988·Acta Orthopaedica Scandinavica·L CarlssonT Albrektsson
Jan 19, 2000·Journal of Pediatric Nursing·M Grey, S Sullivan-Bolyai
Feb 4, 2003·Clinical Oral Implants Research·Daniele BotticelliJan Lindhe
Feb 4, 2003·Clinical Oral Implants Research·Daniele BotticelliJan Lindhe
May 21, 2003·Clinical Oral Implants Research·Tord BerglundhJan Lindhe
Jul 14, 2004·Clinical Oral Implants Research·Ingemar AbrahamssonJan Lindhe
May 5, 2006·Clinical Oral Implants Research·Natalia Lioubavina-HackThorkild Karring
Aug 12, 2009·Clinical Oral Implants Research·Ann Wennerberg, Tomas Albrektsson

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Citations

Feb 22, 2014·International Journal of Oral Science·Rafael Arcesio Delgado-RuizGeorgios Romanos
Sep 30, 2014·Clinical Oral Implants Research·Fabrizio MorelliDaniele Botticelli
Oct 8, 2015·Tissue Engineering. Part C, Methods·Stefano SivolellaBarbara Zavan
May 6, 2020·Journal of Clinical Medicine·Giulia BrunelloStefano Sivolella

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