Osteoimmunology--the hidden immune regulation of bone

Autoimmunity Reviews
J Caetano-LopesJ E Fonseca

Abstract

Osteoimmunology is an emerging field of research dedicated to the investigation of the interactions between the immune and skeletal systems. These interactions are not only mediated by the release of cytokines and chemokines but also by direct cell-cell contact. Recently, it was proposed that immunoreceptors found in the immune cells are also an essential signal for osteoclasts activation, along with receptor activator NF-kappaB (RANK) ligand (RANKL) and macrophage-colony stimulating factor (M-CSF). In addition, adipose tissue also produces several factors (adipokines) that are known to interfere with the immune system and bone homeostasis. Chronic inflammation strongly influences osteoimmunology determining profound metabolic, structural and functional changes in bone.

References

Jun 11, 1996·Proceedings of the National Academy of Sciences of the United States of America·C B Kallen, M A Lazar
Oct 28, 2003·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Hao Wu, Joseph R Arron
Aug 6, 2005·Autoimmunity Reviews·Ruth Y LanM Eric Gershwin
Mar 23, 2006·Annual Review of Immunology·Matthew C WalshYongwon Choi
Aug 8, 2006·Cell Metabolism·Chen ZhaoKoichi Matsuo
Aug 12, 2006·Cell·Gregory R Mundy, Florent Elefteriou
Aug 26, 2006·Nature Clinical Practice. Rheumatology·Clifford J Rosen, Mary L Bouxsein
Nov 8, 2006·The Journal of Experimental Medicine·Kojiro SatoHiroshi Takayanagi
Nov 14, 2006·Bone·Masataka Asagiri, Hiroshi Takayanagi
Feb 10, 2007·Autoimmunity Reviews·Janette Furuzawa-CarballedaAntonio R Cabral
Mar 24, 2007·Nature Reviews. Immunology·Hiroshi Takayanagi
Apr 28, 2007·Biochemical and Biophysical Research Communications·Yong Gil KimHee-Bom Moon
Nov 3, 2007·Nature Cell Biology·Thomas Günther, Roland Schüle
Nov 6, 2007·Trends in Immunology·Daniel S Straus, Christopher K Glass
Nov 27, 2007·Nature Clinical Practice. Rheumatology·Francisca LagoOreste Gualillo
Jan 15, 2008·Autoimmunity Reviews·Julia Hurst, Philipp von Landenberg
Feb 2, 2008·Archives of Biochemistry and Biophysics·Andrea Del FattoreNadia Rucci
Apr 29, 2008·Journal of Clinical Pathology·H K DattaS S Varanasi
May 13, 2008·Trends in Molecular Medicine·Sonja HermanGeorg Schett
May 20, 2008·Autoimmunity Reviews·Nadir AskenasyShai Yarkoni

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Citations

Mar 14, 2012·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Dror Ben-DavidAbraham Z Reznick
Nov 27, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S MorinUNKNOWN Manitoba Bone Density Program
Jan 19, 2011·Cancer Immunology, Immunotherapy : CII·Evangelos Terpos, Meletios A Dimopoulos
Apr 18, 2012·Proceedings of the National Academy of Sciences of the United States of America·Moran ArizonAvi-Hai Hovav
Dec 5, 2013·International Journal of Evidence-based Healthcare·Brian CheeP Mark Bartold
Jan 19, 2010·Arthritis Research & Therapy·Joana Caetano-LopesJoão E Fonseca
Jun 16, 2012·PloS One·Zachary S BuchwaldRajeev Aurora
Aug 2, 2012·Wiener klinische Wochenschrift·Tugrul PurnakMerve Hayretci
Feb 18, 2016·Clinical Oral Investigations·B CheeP M Bartold
Feb 6, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M GuarinoF Morisco
Mar 8, 2011·Medical Hypotheses·Yaozong ZhangLin Chen
Oct 27, 2009·Medical Hypotheses·Ning ZhangWei-Shan Chen
Nov 3, 2009·Nature Reviews. Gastroenterology & Hepatology·Inaam A Nakchbandi, Schalk W van der Merwe
Jun 16, 2010·Acta Paediatrica·R GruodytėT Jürimäe
Nov 11, 2010·Annals of the New York Academy of Sciences·Michael A ViaJeffrey I Mechanick
Apr 5, 2013·Annals of the New York Academy of Sciences·Sonia IyerWilliam G Kerr
Apr 21, 2010·Periodontology 2000·P Mark BartoldDavid R Haynes
May 10, 2013·Oral Diseases·A WilenskyA-H Hovav
May 20, 2016·BioMed Research International·Daniele BollatiRuggero Rodriguez Y Baena
Jan 8, 2015·Cytokine & Growth Factor Reviews·Dimitrios AgasMaria Giovanna Sabbieti
Dec 17, 2014·Cancer Treatment Reviews·Carmen CriscitielloGiuseppe Curigliano
Jun 18, 2010·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Tsai-Pei HsiehMing-Hong Chen
May 12, 2016·Clinical Reviews in Allergy & Immunology·Sofia Carvalho Barreira, João Eurico Fonseca
Sep 18, 2014·PloS One·Aline Lázara ResendeViktoria Woronik
Jan 7, 2017·Journal of Dental Research·Y LiuY H Zhou
Apr 9, 2017·Stem Cells·Fernando A FierroIannis E Adamopoulos
Oct 4, 2011·The Journal of Rheumatology·Ichiro TatsunoTakao Sugiyama
Nov 1, 2018·Journal of Biomedical Materials Research. Part a·Chenyu ChuYili Qu
Jan 30, 2019·Journal of Clinical Medicine·Luis Amengual-PeñafielRicardo Cartes-Velásquez
May 17, 2019·Annals of the New York Academy of Sciences·Yamei XuQingqing Wu

❮ Previous
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