Osteomyelitis

Current Opinion in Rheumatology
R T LaughlinJ H Calhoun

Abstract

The complexities of osteomyelitis make its diagnosis and treatment challenging. Current trends emphasize early diagnosis and aggressive treatment. Imaging has improved, with nuclear scans and magnetic resonance imaging, and technique modifications have enhanced the specificity of these tests. Treatment depends on thorough debridement of necrotic bone and tissue, accurate cultures and administration of culture, and sensitivity-specific antibiotics. Antibiotic delivery has expanded to include effective oral agents and local agents mixed with polymethylmethacrylate or a biodegradable substance. Success rates in treating this disease have improved with the use of a systematic approach, making outcome more predictable.

Citations

Jan 15, 1999·Infectious Disease Clinics of North America·A D Tice
Jul 18, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·S FulliloveJ S Friedland
Jun 1, 1997·International Journal of Antimicrobial Agents·L O Gentry
Apr 13, 2012·American Journal of Clinical Dermatology·Daniel MarchalikSandy S Milgraum
Aug 23, 2001·Scandinavian Journal of Infectious Diseases·M BeroniusR Andersson
Feb 25, 2009·Expert Opinion on Pharmacotherapy·Juan García-Lechuz, Emilio Bouza

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