PMID: 16524553Mar 10, 2006Paper

Osteopenia and osteoporosis in patients with HIV: a review of current concepts

Current Infectious Disease Reports
Todd T Brown, Grace A McComsey

Abstract

Since the advent of potent antiretroviral therapy in combination regimens, multiple epidemiologic studies have shown that osteopenia and osteoporosis are common among patients with HIV infection. However, there remain many areas of uncertainty about this potential complication, which can be confusing for the HIV clinician. This review summarizes the epidemiology, pathophysiology, suggested screening strategies, and management options of decreased bone mineral density in patients with HIV. Our aims are to review the available data, highlight controversial issues, and provide guidance for clinicians where supporting data are unavailable.

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