Abstract
The osteopontin: alphavbeta3 integrin complex has been proposed as a means of distinguishing receptive from non-receptive endometrium in clinical practice, thus offering new directions for the development of contraceptive approaches targeted to the endometrium as well as a better understanding of occult causes of infertility in women. Histological dating and immunohistochemical study were performed in control and study cycles in seven groups of women including 10 subjects per group and who received clomiphene citrate, ovarian stimulation for IVF, oral contraception, dehydrogesterone for endometrial luteal phase defect, two different regimens of hormone replacement therapy, or no treatment. Ten healthy fertile women served as a general control group. Osteopontin and alphavbeta3 integrin expression in the human endometrium was closely related to endometrial maturation and this was irrespective of the endometrium being in-phase or out-of-phase and the hormonal treatment (or no treatment) received. In conclusion, immunohistochemical assessment of the endometrium indicates that the use of osteopontin and alphavbeta3 integrin or the osteopontin: alphavbeta3 integrin complex as targets for the development of contraceptive approaches o...Continue Reading
References
Jun 1, 1992·American Journal of Obstetrics and Gynecology·A J PetersC B Coulam
Jun 1, 1989·Obstetrics and Gynecology·D L Olive
Aug 4, 1998·Human Reproduction·M A HabibaF Al-Azzawi
Nov 30, 2000·The Journal of Clinical Endocrinology and Metabolism·N SantoroG Weiss
Feb 24, 2001·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·H Yaziji, A M Gown
May 22, 2003·Best Practice & Research. Clinical Obstetrics & Gynaecology·Andrew M Sharkey, Stephen K Smith
Jul 28, 2004·American Journal of Reproductive Immunology : AJRI·Zdzisława Kondera-AnaszAleksandra Mielczarek-Palacz
Jan 27, 2005·Reproductive Biomedicine Online·Diederik A HoozemansPeter G A Hompes
Feb 8, 2005·Molecular & Cellular Proteomics : MCP·Mathias Uhlen, Fredrik Ponten
Apr 13, 2005·Reproductive Biomedicine Online·Vasilis MinasAntonis Makrigiannakis
May 20, 2006·Medicinal Research Reviews·Annu Makker, M M Singh
Jun 2, 2006·Molecular & Cellular Proteomics : MCP·Nilofer S AzadElise C Kohn
Jul 13, 2006·Human Reproduction Update·Thomas StrowitzkiM von Wolff
Sep 20, 2006·Human Reproduction Update·Hanna Achache, Ariel Revel
Mar 31, 2007·Reproduction, Fertility, and Development·Sachin S Mangale, K V R Reddy
Jun 5, 2007·Journal of Proteome Research·Haiping PeiHong Shen
Nov 24, 2007·Seminars in Cell & Developmental Biology·L AghajanovaL C Giudice
Jun 14, 2008·Reproductive Biomedicine Online·Gemma CasalsJuan Balasch
Aug 2, 2008·Fertility and Sterility·Qingxiang WeiLynnette K Nieman
Mar 6, 2009·American Journal of Reproductive Immunology : AJRI·SiHyun ChoByung Seok Lee
Jun 27, 2009·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Paulo SerafiniEdmund Chada Baracat
Citations
Jan 5, 2012·Human Reproduction·Gemma CasalsJuan Balasch
Sep 25, 2012·Human Reproduction·Ting XiongHanwang Zhang
Jan 19, 2016·Fertility and Sterility·Elavarasan SubramaniKoel Chaudhury
Jun 13, 2013·Fertility and Sterility·Carol CoughlanSusan Laird
Aug 25, 2011·Fertility and Sterility·Rong ZhangJi-Sheng Han
Sep 2, 2011·Fertility and Sterility·Bruce A Lessey
Jun 1, 2014·Chemico-biological Interactions·Jianhong ZhouJie Zhang
Feb 15, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Yuehui ZhangXiaoke Wu
Apr 5, 2013·PloS One·Sonali R BhagwatGeetanjali Sachdeva
Jan 25, 2014·Reproductive Sciences·Ione Maria Ribeiro Soares LopesJosé Maria Soares
Jan 8, 2016·Dose-response : a Publication of International Hormesis Society·Chiara MannelliLuana Paulesu
Jul 16, 2013·International Journal of Molecular Sciences·Qing-Zhen XieJing Yang
Jan 25, 2020·Expert Review of Clinical Pharmacology·Carlo BastianelliGiuseppe Benagiano
Nov 9, 2016·Human Reproduction·T TatsumiH Saito
Sep 1, 2017·Scientific Reports·Signe AltmäeAndres Salumets
Mar 7, 2012·Experimental Biology and Medicine·Xiaowei WeiQiu Yan
Sep 28, 2017·BMC Women's Health·Ahmed ElnaggarAlaa M Atef
Jul 18, 2020·Reproductive Sciences·Yan LiAijun Zhang
Nov 13, 2020·Frontiers in Immunology·Shalini Gupta, Pawan Gupta
Feb 6, 2021·Reproduction, Fertility, and Development·Tina D Tremaine, Ali A Fouladi-Nashta