Osteoporosis prophylaxis during corticosteroid treatment: failure to prescribe

Postgraduate Medical Journal
S R Hart, B Green

Abstract

To investigate prescribing patterns to prevent steroid induced osteoporosis. To compare prophylactic prescribing with National Osteoporosis Society (NOS) guidelines. All patients (n=92) taking oral corticosteroids admitted to general medical wards at a district general hospital were prospectively investigated over a nine month period. Variations from recommended management were revealed. Altogether 64.7% of all inpatients who qualified for prophylaxis for steroid induced osteoporosis were not provided with any suitable agent. It was also found that 21.6% of those who qualified for treatment received a bisphosphonate, the only treatment currently licensed for preventing steroid induced osteoporosis. Of those prescribed prophylactic treatment, a bisphosphonate was selected for 39.3%, hormone replacement therapy was given to 25.0%, and 35.7% received treatment that is not recommended in NOS guidelines. This study revealed substantial variations from NOS guidelines. It is suggested that osteoporosis prophylaxis during steroid treatment is promoted by local hospital guidelines, hospital and community pharmacists, audit, and general practitioners.

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Citations

May 12, 2005·Rheumatology International·Konstanze LoddenkemperFrank Buttgereit
Apr 9, 2010·International Journal of Rheumatic Diseases·Chanchal Gera, Amarjit Singh Vij
Jul 17, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M DuyvendakJ R B J Brouwers
Feb 5, 2010·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Randy A WalkerRegina M Taylor-Gjevre
Apr 9, 2008·Seminars in Cutaneous Medicine and Surgery·Rosemarie H Liu, Victoria P Werth
Mar 1, 2003·Expert Review of Neurotherapeutics·Ryan L Kaplan, James W Albers
Aug 16, 2006·Seminars in Cutaneous Medicine and Surgery·Rosemarie H Liu, Victoria P Werth
Apr 19, 2005·Treatments in Endocrinology·Ann Cranney, Jonathan D Adachi
May 19, 2009·Annals of Saudi Medicine·Mir Sadat-AliMohammed A Abujubara
Mar 1, 2005·Irish Journal of Medical Science·J G RyanP G O'Connell

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