Osteopromotion Capacity of Bovine Cortical Membranes in Critical Defects of Rat Calvaria: Histological and Immunohistochemical Analysis

International Journal of Biomaterials
Carolina Ferrairo Danieletto-ZannaAna Paula Farnezi Bassi

Abstract

Membranes that aid the guided bone regeneration (GBR) process have been the subject of studies of compatible biomaterials that contribute to this repair process. The present study compared different membranes used in critical-size defects of rat calvaria by assessing GBR as well as histological, histomorphometric, and immunohistochemical reactions. Forty-eight male albino Wistar rats were randomly allocated into four groups (n = 12 each), namely, C: membrane-free control group (only blood clot, negative control group); BG: porcine collagen membrane group (Bio-Gide®, positive control group); GD: bovine cortical membrane group (first experimental group); and GDF: thicker bovine cortical membrane group (second experimental group). Rats were euthanized at 30 and 60 days postoperatively. Quantitative data from the histometric analysis were submitted to two-way ANOVA and Tukey's posttest when p < 0.05. Histomorphometric results of the thicker bovine cortical membrane at 30 and 60 days were promising, showing improved new bone formation values (p < 0.05), and the CD group presented similar results in both analysis periods, being surpassed only by the GDF group (p < 0.05). The immunohistochemical results were associated with the histom...Continue Reading

References

Dec 1, 1990·Clinical Oral Implants Research·D BuserS Nyman
Jan 1, 1994·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·H SchliephakeJ Becker
Apr 21, 2001·The Journal of Craniofacial Surgery·S StalL Hollier
Dec 19, 2007·Journal of Biomedical Materials Research. Part a·Jin-Woo ParkChong-Soo Lee
Mar 25, 2009·Clinical Oral Implants Research·Jin-Woo ParkJo-Young Suh
Mar 23, 2011·Journal of Materials Science. Materials in Medicine·Thais Accorsi-MendonçaJosé Mauro Granjeiro
Jun 8, 2013·Clinical Oral Implants Research·André VajgelNikolaos Donos
Oct 26, 2013·Journal of Dental Research·V ChappuisD Buser
Oct 30, 2013·Journal of Clinical Periodontology·Jesús Torres García-DencheFaleh Tamimi
Jun 5, 2014·The Open Dentistry Journal·Jie Liu, David G Kerns
Feb 4, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Neusa M F CostaJosé M Granjeiro
Mar 14, 2017·Implant Dentistry·Juceléia MacielAna Paula Farnezi Bassi
Aug 24, 2017·European Journal of Oral Sciences·Ibrahim ElgaliPeter Thomsen

❮ Previous
Next ❯

Citations

Sep 17, 2020·Membranes·Ana Paula Farnezi BassiFlavia de Almeida Lucas
Feb 13, 2021·Membranes·Ana Paula Farnezi BassiLeonardo Perez Faverani

❮ Previous
Next ❯

Methods Mentioned

BETA
optical microscopy

Software Mentioned

SigmaPlot
ARRIVE
ImageJ
GenDerm

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
Yu-Bin CaoCheng-Ge Hua
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Xiaomin Wang, Xudong Li
© 2021 Meta ULC. All rights reserved