Osteosarcoma of the jaw: Challenges in the diagnosis and treatment

Journal of the Egyptian National Cancer Institute
Mohamed Atef ElKordyAyman Abd ElWahab Amin

Abstract

Osteosarcomas rarely affect jaw bones. Patients are usually older than those who suffer long bone sarcomas, with a rare incidence of metastasis. This is suggestive of a different pattern of behavior compared with long bone sarcomas. This study aimed to present NCI, Cairo University experience in treating patients diagnosed with osteosarcomas of the jaw, including the diagnostic challenges and treatment outcome. This is a retrospective case series study of all cases of osteosarcomas of mandible and maxilla that were treated at the NCI, in the period between 2006 and 2013. Patients' data, including demographic data, various clinical presentations, results of investigations, treatment modalities performed and outcomes, were collected from hospital records kept in the Biostatistics Department at NCI. Records showed 21 cases of osteosarcoma of the jaw. The mandible was affected in 15 cases, the maxilla in six. Two cases had sun-ray periosteal reactions. Erroneous biopsy results were found in 4 cases compared with final pathology reports of surgical resections. All cases underwent surgical resections, with 8 cases having positive margins. The median follow-up period was 19.3 months (range 0.3-98.0 months). The cumulative disease-free...Continue Reading

References

Nov 1, 1996·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·O AltuwairgiD D Karp
Jan 1, 1997·The Laryngoscope·R R KassirJ A Hokanson
Feb 6, 2002·Skeletal Radiology·Richard H DaffnerKentR Galey
Apr 22, 2005·The Journal of Otolaryngology·UNKNOWN Canadian Society of Otolaryngology-Head and Neck Surgery Oncology Study Group
May 18, 2005·Dento Maxillo Facial Radiology·E NakayamaK Yoshiura
Dec 20, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Mobolanle Olugbemiga OgunleweOlutayo James
Apr 1, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Leo KagerUNKNOWN Cooperative Osteosarcoma Study Group
May 1, 2007·Oral Oncology·Sven JasnauUNKNOWN Cooperative Osteosarcoma Study Group COSS
Apr 22, 2009·Cancer·B Ashleigh GuadagnoloErich M Sturgis
May 5, 2010·Journal of Cancer Research and Clinical Oncology·Y YamamotoH Yamada
Feb 4, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Megan Granowski-LeCornuMeredith August
Dec 19, 2013·Cancer Treatment Reviews·Anja LuetkeHeribert Juergens
Feb 4, 2014·CA: a Cancer Journal for Clinicians·Elizabeth WardAhmedin Jemal

❮ Previous
Next ❯

Citations

Mar 21, 2020·Cell Biochemistry and Function·Wei LiuMing Yan
Jan 18, 2020·Head and Neck Pathology·Ngoc-Anh TranJyothi Jagannathan
May 15, 2020·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Faizan MalikShweta Agarwal
Aug 10, 2020·Current Medical Imaging·Francesco RicottaAchille Tarsitano
Jul 30, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Wei HanWei Guan
Aug 3, 2021·Frontiers in Cell and Developmental Biology·Xinwen WangXiaochun Bai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical and Diagnostic Research : JCDR
Jitendra V KalburgeYogesh Kini
Journal of Neurosurgical Sciences
B ChanderC Sarkar
Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
D S VegeB Bhaser
© 2022 Meta ULC. All rights reserved