Otogenic cerebral venous thrombosis in children: A review of 16 consecutive cases

International Journal of Pediatric Otorhinolaryngology
Gil CoutinhoJorge Spratley

Abstract

Management of otogenic cerebral venous thrombosis (OCVT) is controversial. Despite the modern antibiotic era OCVT still represents a potential life-threatening condition. This study aims to report the clinical presentation and management in a series of children with OCTV. The coexisting intracranial complications (ICC), the extent of the surgical treatment and the role of hypocoagulation were the analysed outcomes. Retrospective chart review of patients aged less than 16 years and consecutively treated for OCVT at a tertiary university hospital between January 2007 and March 2015. Sixteen children with ages ranging between 25 months and 16 years (9 girls/7 boys) with OCVT were identified. Acute otitis media was the causative factor in the majority of cases (n = 13). The remaining cases resulted from chronic otitis media with cholesteatoma (COMC). Eleven patients were under antibiotic therapy prior to admission. Other ICC were simultaneously present: intracranial abscess (n = 6); otitic hydrocephalus (n = 3); and meningitis (n = 1). Thrombus extension correlated with the presence of additional ICC (p = 0.035). Treatment in all cases comprised of broad-spectrum antibiotics, mastoidectomy, and long-range hypocoagulation with warfa...Continue Reading

Citations

Mar 15, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Brittany N BurtonJeffrey P Harris
Aug 4, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nathan A ShlobinSandi Lam
Sep 5, 2020·Italian Journal of Pediatrics·Massimo Luca CastellazziPaola Marchisio
Sep 15, 2020·International Journal of Pediatric Otorhinolaryngology·Erdem Duygu, Sultan Şevik Eliçora
May 21, 2021·Diabetes & Metabolic Syndrome·Ritwik GhoshJulián Benito-León
Oct 27, 2021·The Journal of Laryngology and Otology·J D Constable, D Hajioff

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