Ototoxicity of baby oil in a chinchilla animal model

International Journal of Pediatric Otorhinolaryngology
A Al-JarallahSam J Daniel

Abstract

Baby oil is commonly used to soften ear wax in order to aid its removal. The aim of this study was to determine the potential ototoxicity of baby oil. A prospective controlled animal study was conducted using ten chinchillas with normal hearing function. Each had bilateral myringotomies. One ear was randomly assigned to receive 1 ml of baby oil while the other ear received an equal volume of 0.45% NaCl. Distortion product otoacoustic emissions (DPOAEs) and Auditory Brainstem Response (ABR) measurements were recorded at baseline (post myringotomy and pre application of product) and on days 5 and 15 after application. Two months after application of baby oil, the cochleae were processed for light microscopy and qualitative comparisons were made between the cochleae of both control and experimental ears. There was no statistically significant difference in DPOAE between experimental and control ears at 5 and 15 days after treatment. ABR results did not reveal ototoxicity at days 5 and 15 post treatment. None of the animals developed facial paralysis or any signs of vestibular toxicity. There were no overt mucosal changes in the middle ear of the ears exposed to baby oil compared to the control ears. Light microscopy showed compara...Continue Reading

References

Nov 14, 1997·Journal of the American Animal Hospital Association·P D MansfieldA E Marshall
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Aug 19, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sam J DanielFadi Akache

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Citations

Dec 3, 2014·International Journal of Pediatric Otorhinolaryngology·Aren BezdjianSam J Daniel
Mar 16, 2013·Clinical Pediatrics·Paul Hong, Neil K Chadha
Mar 29, 2019·American Journal of Veterinary Research·Fiona L BatemanJoerg Mayer

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