PMID: 6983809Nov 1, 1982Paper

Ototoxicity of netilmicin

Acta Oto-laryngologica
O TjernströmN G Toremalm

Abstract

Ototoxicity and efficacy of netilmicin was evaluated in 76 consecutive patients with moderate to severe infections with Gram-negative rods and Staphylococcus aureus. Netilmicin alone was efficacious in 47 patients and in another 23 patients cure or improvement was seen with netilmicin combined with another antibiotic, usually penicillin. Therapeutic failure was seen in 4 cases, 2 of which were regarded as netilmicin failures. Vestibular function and hearing acuity was thoroughly examined by electronystagmography and audiometry. In spite of the extensive examination of the audiovestibular function it was possible to detect only one probable case of ototoxicity related to netilmicin, a reversible vestibular dysfunction. The importance of pre-therapeutic audiovestibular examination is stressed.

References

Sep 1, 1976·Antimicrobial Agents and Chemotherapy·K P Fu, H C Neu
Apr 1, 1976·Antimicrobial Agents and Chemotherapy·J J RahalN H Moldover
Aug 1, 1976·Antimicrobial Agents and Chemotherapy·C Watanakunakorn
Jun 1, 1976·Antimicrobial Agents and Chemotherapy·R E BlackW L Hewitt
Nov 1, 1976·Antimicrobial Agents and Chemotherapy·G H MillerJ A Waitz
Nov 1, 1976·Antimicrobial Agents and Chemotherapy·F C LuftS A Kleit
Jan 1, 1976·Infection·P Federspil
Aug 1, 1976·The Journal of Infectious Diseases·H C Neu, C L Bendush
Jan 1, 1975·The Annals of Otology, Rhinology, and Laryngology·C A Quick, W Hoppe
Jul 1, 1975·Acta Oto-laryngologica·R E BrummettD Himes
Sep 1, 1973·Audiology : Official Organ of the International Society of Audiology·H StuppM Quante
Aug 1, 1970·Archives of Otolaryngology·R M Meyers
May 1, 1980·The Journal of Laryngology and Otology·R T RamsdenW P Gibson
Jan 1, 1980·Acta Oto-laryngologica·M Anniko

❮ Previous
Next ❯

Citations

Aug 1, 1990·Toxicology Letters·P J GovaertsM E De Broe
Jun 1, 1989·Antimicrobial Agents and Chemotherapy·R E Brummett, K E Fox
Jul 24, 2008·The Annals of Pharmacotherapy·Robert E ArianoDiamond A Kassum
Jun 27, 2017·Ear and Hearing·Ruth Van HeckeLeen Maes
Nov 1, 1989·Medical Toxicology and Adverse Drug Experience·M Y Huang, J Schacht

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Antimicrobial Agents and Chemotherapy
I TrestmanD Kaye
Clinical Otolaryngology and Allied Sciences
A P Walby, A G Kerr
Issues in Comprehensive Pediatric Nursing
J H Boffman
© 2021 Meta ULC. All rights reserved