Our genes are not our destiny: incorporating molecular medicine into clinical practice

Journal of Evaluation in Clinical Practice
Stephen J Genuis

Abstract

In many developed nations, the state of publicly administered health care is increasingly precarious as a result of escalating numbers of chronically ill patients, inadequate medical personnel and hospital facilities, as well as sparse funding for ongoing upgrades to state-of-the-art diagnostic and therapeutic technology - an increased emphasis on aetiology-centred medicine should be considered in order to achieve improved health for patients and populations. Medical practice patterns which are designed to provide quick and effective amelioration of signs and symptoms are frequently not an enduring solution to many health afflictions and chronic disease states. Recent scientific discovery has rendered the drug-oriented algorithmic paradigm commonly found in contemporary evidence-based medicine to be a reductionist approach to clinical practice. Unfolding evidence appears to support a genetic predisposition model of health and illness rather than a fatalistic predestination construct - modifiable epigenetic and environmental factors have enormous potential to influence clinical outcomes. By understanding and applying fundamental clinical principles relating to the emerging fields of molecular medicine, nutrigenomics and human ex...Continue Reading

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Citations

May 15, 2009·International Journal of Environmental Research and Public Health·Stephen J GenuisSharon A Vaselenak
Aug 17, 2011·International Journal of Environmental Research and Public Health·Chiara De LucaLiudmila Korkina
Apr 16, 2011·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Linn GetzElling Ulvestad
Feb 9, 2012·Journal of Environmental and Public Health·Margaret E Sears, Stephen J Genuis
Jul 14, 2010·Public Health·S J GenuisN Thibault
Jul 16, 2008·Neurotoxicology·Stephen J Genuis
Jan 16, 2016·Obstetrics and Gynecology International·Stephen J Genuis
Oct 22, 2009·Acta Paediatrica·S J Genuis
Mar 6, 2010·Pediatrics International : Official Journal of the Japan Pediatric Society·Stephen J Genuis
Jun 18, 2016·BioMed Research International·Stephen J Genuis, Rebecca A Genuis
Apr 28, 2017·Toxicology Mechanisms and Methods·Stephen J Genuis, Edmond Kyrillos
Jun 22, 2019·Journal of Advanced Nursing·Nicola DoverBrendan Garry
Apr 25, 2019·International Journal of Environmental Research and Public Health·Nufail KhanSusan Brumby

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