Out-of-Hospital Research in the Era of Electronic Health Records

Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors
Craig D NewgardDana Zive

Abstract

Conducting out-of-hospital research is unique and challenging and requires tracking patients across multiple phases of care, using multiple sources of patient records and multiple hospitals. The logistics and strategies used for out-of-hospital research are distinct from other forms of clinical research. The increasing use of electronic health records (EHRs) by hospitals and emergency medical services (EMS) agencies presents a large opportunity for accelerating out-of-hospital research, as well as particular challenges. In this study, we describe seven key aspects of designing and implementing out-of-hospital research in the era of EHRs: (1) selection of research sites, (2) defining the patient population, (3) patient sampling and sample size calculations, (4) EMS data, (5) hospital selection, (6) handling missing data, and (7) statistical analysis. We use examples from a recent prospective out-of-hospital cohort study to illustrate these topics, including lessons learned.

References

Apr 1, 1996·Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses·S Schreiber
Apr 19, 2002·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Craig D Newgard, Roger J Lewis
Apr 12, 2003·Forensic Science International : Synergy·Yasemin GünayBurcu Eşiyok
Jun 28, 2006·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Drew E Dawson
Jan 29, 2008·Journal of the American College of Surgeons·Karen J BraselUNKNOWN Resuscitation Outcomes Consortium Investigators
May 16, 2008·Resuscitation·Laurie J MorrisonUNKNOWN ROC Investigators
Oct 7, 2010·JAMA : the Journal of the American Medical Association·Eileen M BulgerUNKNOWN ROC Investigators
Feb 11, 2012·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Craig D NewgardMohamud Daya
Apr 18, 2012·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Robert SilbergleitUNKNOWN NETT Investigators
Apr 18, 2012·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Craig NewgardUNKNOWN WESTRN investigators
Jan 1, 2012·Medicare & Medicaid Research Review·Gerald F Riley
Mar 26, 2015·The Journal of Trauma and Acute Care Surgery·Martin A SchreiberUNKNOWN ROC Investigators
Dec 30, 2015·Journal of the American College of Surgeons·Craig D NewgardEileen Bulger
Sep 23, 2016·JAMA : the Journal of the American Medical Association·Harold C Sox, Roger J Lewis
Aug 10, 2017·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·So Yeon KongJames F Holmes
Sep 15, 2017·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Robert SworWilliam Fales

❮ Previous
Next ❯

Citations

Feb 1, 2019·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Colleen J BresslerJulie C Leonard
Mar 20, 2019·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Jessica K Zègre-HemseyJane Brice
Dec 26, 2018·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Joanne CosterJanette Turner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Emergency Medicine
Daniel A Handel, Jeffrey L Hackman
The New England Journal of Medicine
T D Valenzuela, M K Copass
Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine
Craig D NewgardROC Investigators
© 2022 Meta ULC. All rights reserved