PMID: 9007958Nov 1, 1996Paper

Outbreak of gentamicin-resistant Acinetobacter baumanii in an intensive care unit: clinical, epidemiological and microbiological features

Pathology
T V RileyR A Bowman

Abstract

The clinical, epidemiological and microbiological features of an outbreak of infection and colonisation caused by gentamicin-resistant Acinetobacter baumanii (GRAB) in an 18-bed intensive care unit (ICU) of a 680-bed adult teaching hospital are described. A retrospective review of medical, laboratory and infection control records was followed by prospective surveillance. Typing of isolates was performed by restriction enzyme analysis (REA) of chromosomal DNA. The incidence of GRAB in the ICU increased from 1.26 cases per 1000 occupied bed days (OBDs) for January to June 1993, to 6.62 per 1000 OBDs for July to December 1993 (Chi square = 4.8, P < 0.05), confirming the existence of an outbreak. For the two year period, 1993 and 1994, a total of 45 cases of GRAB infection or colonisation was identified. Males and females were equally represented, with an age range of 16-79 years and a mean age of 51 years. Admitting diagnoses varied, with multiple trauma and head injury predominating (ten cases). For 35 of the 45 cases the initial site of GRAB isolation was sputum or other respiratory tract specimen. Specific treatment for GRAB was initiated in 23 patients, however no deaths were directly attributable to GRAB infection. The period...Continue Reading

References

Jun 1, 1991·The Journal of Hospital Infection·E Bergogne-Bérézin, M L Joly-Guillou
Dec 1, 1991·Epidemiology and Infection·G L O'NeillT V Riley
Oct 1, 1990·American Journal of Epidemiology·C M Beck-SaguéM P Weinstein
Jun 29, 1989·The New England Journal of Medicine·B S KleinD G Maki
Jun 1, 1988·American Journal of Infection Control·J S GarnerJ M Hughes
Sep 1, 1987·The Journal of Hospital Infection·E Bergogne-BérézinJ F Vieu
Oct 1, 1985·American Journal of Infection Control·D H Gervich, C S Grout
Mar 1, 1980·Postgraduate Medical Journal·B A CunhaR Quintiliani
Jun 14, 1980·British Medical Journal·M A Burrow, P J Redding
Feb 1, 1993·The Journal of Hospital Infection·A KropecF D Daschner
Jun 1, 1993·Journal of Clinical Pathology·L DijkshoornA M Horrevorts

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Citations

Jun 18, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D H Forster, F D Daschner
Jul 30, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J Monterrubio-VillarJ A Saéz-Nieto
Jan 7, 2004·The Journal of Hospital Infection·V Damjanovic, H K F van Saene
Jun 20, 2003·Lancet·Jean-Louis Vincent
Dec 22, 1999·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·I S PetersenO B Jepsen
Jul 16, 2008·Clinical Microbiology Reviews·Anton Y PelegDavid L Paterson
Oct 19, 2007·The Journal of Hospital Infection·C MarshallD Spelman
Oct 21, 2006·The Journal of Hospital Infection·V Damjanovic, H K F van Saene
Jul 27, 2006·Internal Medicine Journal·A Y Peleg, D L Paterson
Mar 22, 2005·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·M DentonP Murphy
Jun 8, 1999·American Journal of Infection Control·P VillariU Bosco
Feb 16, 2002·The Journal of Hospital Infection·I DasT Elliott
Jul 13, 2014·International Journal of Surgery Case Reports·Aqsa AliRavindranath Tiruvoipati
Jan 16, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Abdel Moati Kh Al JaroushaIyad A El Qouqa
May 3, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Maria Virginia Villegas, Alan I Hartstein
May 3, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Cosmina ZeanaPhyllis Della-Latta
Jul 12, 2001·Clinical & Experimental Ophthalmology·K M CorriganM D Willcox
Sep 13, 2002·The Medical Journal of Australia·Peter J Collignon
Feb 3, 2000·Journal of Clinical Microbiology·A TakahashiS Iyobe

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