Outbreaks of highly pathogenic avian influenza H5N1 clade 2.3.2.1c in hunting falcons and kept wild birds in Dubai implicate intercontinental virus spread

The Journal of General Virology
Mahmoud M NaguibTimm C Harder

Abstract

Highly pathogenic avian influenza viruses (HPAIVs) of subtype H5N1 have continued to perpetuate with divergent genetic variants in poultry within Asia since 2003. Further dissemination of Asian-derived H5 HPAIVs to Europe, Africa and, most recently, to the North American continent has occurred. We report an outbreak of HPAIV H5N1 among falcons kept for hunting and other wild bird species bred as falcon prey in Dubai, United Arab Emirates, during the autumn of 2014. The causative agent was identified as avian influenza virus subtype H5N1, clade 2.3.2.1c, by genetic and phylogenetic analyses. High mortality in infected birds was in accordance with systemic pathomorphological and histological alterations in affected falcons. Genetic analysis showed the HPAIV H5N1 of clade 2.3.2.1c is a reassortant in which the PB2 segment was derived from an Asian-origin H9N2 virus lineage. The Dubai H5N1 viruses were closely related to contemporary H5N1 HPAIVs from Nigeria, Burkina-Faso, Romania and Bulgaria. Median-joining network analysis of 2.3.2.1c viruses revealed that the Dubai outbreak was an episode of a westward spread of these viruses on a larger scale from unidentified Asian sources. The incursion into Dubai, possibly via infected capt...Continue Reading

References

May 20, 1999·Molecular Biology and Evolution·H J BandeltA Röhl
Aug 27, 2002·Nature Medicine·Sang Heui SeoRobert G Webster
May 27, 2005·Nature·Robert Webster, Diane Hulse
Dec 26, 2008·Journal of Clinical Microbiology·Dirk HöperMartin Beer
Dec 18, 2009·The Journal of General Virology·Jin Hyun KimYoshihiro Kawaoka
Dec 24, 2009·Antimicrobial Agents and Chemotherapy·Varough M DeydeLarisa V Gubareva
Apr 26, 2011·Virology Journal·Andrea KohlsMichael Lierz
Nov 1, 2011·Influenza and Other Respiratory Viruses·UNKNOWN WHO/OIE/FAO H5N1 Evolution Working Group
Dec 2, 2011·Annual Review of Food Science and Technology·Revis Chmielewski, David E Swayne
Jan 19, 2013·Molecular Biology and Evolution·Kazutaka Katoh, Daron M Standley
Feb 19, 2013·Molecular Biology and Evolution·Bui Quang MinhArndt von Haeseler
Jul 31, 2013·Influenza and Other Respiratory Viruses·Ulrich WerneryRobert G Webster
Apr 24, 2014·Emerging Infectious Diseases·Kanti PabbarajuGraham A Tipples
May 2, 2014·Nucleic Acids Research·Marco BiasiniTorsten Schwede
Jun 14, 2014·Epidemiology and Infection·G ClaesS Marché
Jun 21, 2014·International Journal of Environmental Research and Public Health·Zhijie ZhangChenglong Xiong
Nov 6, 2014·Molecular Biology and Evolution·Lam-Tung NguyenBui Quang Minh
Apr 11, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·A S ArafaT C Harder
Apr 22, 2015·Emerging Infectious Diseases·Hon S IpJonathan M Sleeman
May 13, 2015·Influenza and Other Respiratory Viruses·Gavin J D SmithUNKNOWN World Health Organization/World Organisation for Animal Health/Food and Agriculture Organization (WHO/OIE/FAO) H5 Evolution
Jun 17, 2015·Emerging Infectious Diseases·Isabella MonneGiovanni Cattoli

❮ Previous
Next ❯

Citations

Mar 5, 2016·Archives of Virology·V Y MarchenkoA B Ryzhikov
May 14, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Chakradhar ToshDiwakar D Kulkarni
Jul 9, 2016·Emerging Infectious Diseases·Luca TassoniIsabella Monne
Nov 23, 2017·EcoHealth·Anne-Lise Chaber
Jul 4, 2020·Avian Pathology : Journal of the W.V.P.A·Yukiko UnoTsuyoshi Yamaguchi
Jan 14, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Mahmoud M NaguibTimm C Harder
Jan 16, 2020·Ecology and Evolution·Justin J S WilcoxYoussef Idaghdour
Sep 16, 2018·Viruses·Ahmed MostafaStephan Pleschka
Mar 15, 2019·Emerging Microbes & Infections·Chavely Gwladys MonamelePhilippe Dussart
Oct 16, 2017·EFSA Journal·UNKNOWN EFSA Panel on Animal Health and Welfare (AHAW)Jan Arend Stegeman
Aug 14, 2020·Vaccines·Ni Luh Putu Indi DharmayantiDiana Nurjanah
Oct 11, 2020·Vaccines·Nongluk Sriwilaijaroen, Yasuo Suzuki

❮ Previous
Next ❯

Related Concepts