Outbreeding selects for spiteful cytoplasmic elements.

Proceedings. Biological Sciences
Jan Engelstädter, Sylvain Charlat

Abstract

In addition to their nuclear genome, the vast majority of eukaryotes harbour cytoplasmic genomes, e.g. in mitochondria or chloroplasts. In the majority of cases, these cytoplasmic genomes are transmitted maternally only, leading to selective pressures divergent from those that act on nuclear genes. In particular, cytoplasmic genes, which reduce the fitness of males that carry them, but have no fitness effect in females, are believed to be selectively neutral. Here, we go a step further and argue that in outbreeding populations (i.e. populations with inbreeding avoidance), 'spiteful' cytoplasmic elements that reduce the number of offspring produced by males are in fact selected for. We study this process by means of a stochastic model, analysing both the probability of spread and the impact that such a spiteful cytotype can have on population dynamics. Our results demonstrate that the probability of spread of the spiteful cytotype can be several times higher in outbreeding than in panmictic populations. Spread and fixation of the spiteful cytotype can lead to different qualitative effects on the population dynamics, including extinction, decreased or increased stable population size. We discuss our results in respect to cytoplas...Continue Reading

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Citations

May 14, 2009·Heredity·J Engelstädter, A Telschow
May 8, 2008·BMC Evolutionary Biology·Max ReuterFrédéric Guillaume
Jun 10, 2009·Journal of Theoretical Biology·Robert L Unckless, Jeremy K Herren
Mar 14, 2007·Evolution; International Journal of Organic Evolution·Solveig Schjørring, Ilonka Jäger
Jan 22, 2009·Evolution; International Journal of Organic Evolution·Ralph Haygood, Michael Turelli
Jan 22, 2009·Evolution; International Journal of Organic Evolution·Michael J Wade, Yaniv Brandvain
Jan 27, 2012·Evolution; International Journal of Organic Evolution·Philip W Hedrick
Jan 11, 2011·Molecular Ecology·Stephan GreinerReinhold G Herrmann
Oct 3, 2012·Evolution; International Journal of Organic Evolution·Hui ZhangJan Engelstädter
Jan 19, 2018·Proceedings. Biological Sciences·Tim ConnallonDamian K Dowling
Jul 25, 2019·Journal of Evolutionary Biology·David Treanor, William O H Hughes
Oct 28, 2019·Journal of Evolutionary Biology·Thomas A KeaneyLuke Holman

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