Outcome after corticoamygdalohippocampectomy in patients with refractory temporal lobe epilepsy and mesial temporal sclerosis without preoperative ictal recording

Epilepsia
Arthur CukiertPedro Paulo Mariani

Abstract

We report on the surgical outcome obtained in patients with refractory temporal lobe epilepsy with mesial temporal sclerosis (MTS) who were evaluated preoperatively without ictal recording and were submitted to corticoamygdalohippocampectomy. Two hundred twelve patients with refractory temporal lobe epilepsy were evaluated by means of clinical history, neurological examination, interictal electroencephalography (EEG), magnetic resonance imaging (MRI), and neuropsychological testing. MRI disclosed unilateral MTS in all patients. All patients were submitted to corticoamygdalohippocampectomy at the side determined by MRI. Interictal EEG showed unilateral temporal lobe spiking in 176 patients; in 36 patients, bilateral discharges were found. Mean follow-up time was 2.7 years. One hundred ninety-four patients (92%) were classified as Engel's class I. Eighteen patients (8%) were rated as Engel's class II. Thirty-two out of 36 patients, in whom bilateral discharges were found, were in Engel's class I. Sixty percent of the patients had an improvement in memory function related to the nonoperated temporal lobe. Fifty-nine percent of the patients had a 10-point increase in general IQ postoperatively. Verbal memory decline was noted in th...Continue Reading

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Citations

Aug 6, 2013·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Nermin G SirinAysen Gokyigit
Jun 24, 2014·Epilepsy Research·Leena JutilaReetta Kälviäinen
Sep 25, 2010·Epilepsy Research·Marcel HeersHermann Stefan
May 29, 2013·Seizure : the Journal of the British Epilepsy Association·Rainer Surges, Christian E Elger
Jun 6, 2009·Seizure : the Journal of the British Epilepsy Association·Arthur CukiertPedro Paulo Mariani
May 25, 2010·Seizure : the Journal of the British Epilepsy Association·Arthur CukiertValeria Antakli Mello
Oct 5, 2010·Epilepsy & Behavior : E&B·Barbara A Dworetzky, Claus Reinsberger
Jul 31, 2019·International Journal of Preventive Medicine·Jafar Mehvari HabibabadiNasim Tabrizi
Mar 5, 2021·Scientific Reports·Muhamad Thohar ArifinZainal Muttaqin
Nov 3, 2017·Seizure : the Journal of the British Epilepsy Association·Yun Jung HurDouglas R Nordli

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