PMID: 25743789Mar 7, 2015Paper

Outcome after simultaneous resection of gastric primary tumour and synchronous liver metastases: survival analysis of a single-center experience in China

Asian Pacific Journal of Cancer Prevention : APJCP
Qian LiuZheng Wang

Abstract

The optimal surgical strategy for the treatment of synchronous resectable gastric cancer liver metastases remains controversial. The aims of this study were to analyze the outcome and overall survival of patients presenting with gastric cancer and liver metastases treated by simultaneous resection. Between January 1990 and June 2009, 35 patients diagnosed with synchronous hepatic metastases from gastric carcinoma received simultaneous resection of both primary gastric cancer and synchronous hepatic metastases. The clinicopathologic features and the surgical results of the 35 patients were retrospectively analyzed. The 5-year overall survival rate after surgery was 14.3%. Five patients survived for more than 5 years after surgery. No mortality has occurred within 30 days after resection, although two patients (5.7%) developed complications during the peri-operative course. Univariate analysis revealed that patients with the presence of lymphovascular invasion of the primary tumor, bilateral liver metastasis and multiple liver metastases suffered poor survival. Lymphovascular invasion by the primary lesion and multiple liver metastases were significant prognostic factors that influenced survival in the multivariate analysis (p=0....Continue Reading

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Citations

May 23, 2019·Molecular Medicine Reports·Yü LiuQun Zhao
Jan 11, 2020·Frontiers in Oncology·Zai LuoChen Huang
Nov 12, 2015·World Journal of Gastroenterology : WJG·Guido Alberto Massimo TiberioUNKNOWN Italian Research Group for Gastric Cancer

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