Outcome and predictive factors of acute renal failure in the intensive care unit

Transplantation Proceedings
B BerniehH El Jack

Abstract

The development of acute renal failure (ARF) in the ICU setting carries a high morbidity and mortality. To assess the outcomes and its predictive factors in our ICU, we analyzed the data of patients with ARF treated during 18 months. The 33 patients included 21 men and 12 women of mean age 51 +/- 21.7 years (13 to 87). Sepsis with multi-organ dysfunction (MOD) was the leading cause of ARF (58%). Comorbid conditions were malignancy in 30% of patients, diabetes mellitus in 24%, hypertension in 21%, ischemic heart disease in 21%, liver disease in 15%, and chronic renal failure in 15%. Predisposing factors were hypotension in 67% of cases, dehydration in 36%, drug related in 33%, congestive heart failure in 24%, and liver cirrhosis in 6%. Twenty-five (76%) patients needed mechanical ventilation, 22 (67%) were anuric, 18 (55%) had MODS, and 15 (45%) needed inotropic support. Length of stay in hospital was 27.2 +/- 28.0 days (2 to 94). Nineteen patients (58%) were managed conservatively and 14 (42%) by renal replacement therapy. Patient mortality was 67% and renal mortality 52%. The impact of the following factor: was assessed on patient and renal outcome was assessed ventilation support, presence of oliguria, need for inotropes, and...Continue Reading

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Citations

Feb 18, 2014·Journal of Critical Care·Sumayah Abdul-JabbarRob Shulman
Jan 29, 2005·Intensive Care Medicine·M E OstermannUNKNOWN Riyadh ICU Program Users Group
Nov 7, 2006·Critical Care : the Official Journal of the Critical Care Forum·Viktoria D MayrWalter R Hasibeder
Sep 12, 2013·Journal of Veterinary Internal Medicine·G SegevJ L Westropp
Mar 27, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michael BedfordPaul Stevens
Jun 21, 2008·Advances in Chronic Kidney Disease·Ryan Goldberg, Paula Dennen
Oct 29, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Azra Bihorac, Edward A Ross
Jul 21, 2006·Journal of Clinical Pharmacology·S BiswalP Pandhi
Nov 9, 2010·The International Journal of Pharmacy Practice·Mahkam TavallaeeShirin Kiani
Jun 25, 2015·Journal of the American Medical Informatics Association : JAMIA·Robert M CroninMichael E Matheny
Oct 16, 2009·Critical Care Medicine·Paula DennenRobert Anderson
Apr 11, 2008·Critical Care Medicine·Chirag R Parikh, Prasad Devarajan
Aug 15, 2006·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·S E MatalounJ L G Amaral

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