Outcome in adult patients with head and neck sarcomas--a 10-year analysis

Journal of Surgical Oncology
Thomas MückeAnastasios Kanatas

Abstract

Sarcomas of the head and neck in adults are malignant tumors with many histological subtypes and sites of origin. The purpose of this study was to analyze the outcome of adult patients suffering from head and neck sarcomas and to identify any clinical and histological predictors of outcome. The medical records of 74 patients treated during 1999-2008 were reviewed. All patients suffered from primary head and neck sarcomas. The mean survival of patients was 44.49 +/- 32.25 months. The 2- and 5-year overall survival rates were 83.78% and 60.81%. The nodal status (P = 0.032), tumor size (P < 0.0001), tumor location (P = 0.03), histological type (P = 0.002), the involvement of bone (P = 0.032), and age (P < 0.0001) were significant parameters influencing survival. This study demonstrated a better than expected crude overall survival and a higher rate of recovery of involved regional lymph nodes with evidence of poorer outcome when cervical metastases are evident. It is suggested that this may reflect the impact of specialist head and neck surgical techniques (applicable to all head and neck malignancy) as well as the recognized need for specialization in pathology and nonsurgical oncology in the care of these patients.

References

Oct 1, 1990·American Journal of Surgery·A I FarhoodE W Strong
Aug 15, 1985·Cancer·J A GreagerT K Das Gupta
Sep 1, 1994·Seminars in Surgical Oncology·J H Edmonson
Jun 1, 1994·Journal of Surgical Oncology·L P Kowalski, C I San
Sep 1, 1994·Archives of Otolaryngology--head & Neck Surgery·J Le VayJ Simm
Jul 1, 1993·British Journal of Cancer·R A EelesC L Harmer
Oct 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·S CakirS Okkan
Feb 15, 2001·American Journal of Otolaryngology·S G PatelJ P Shah
May 2, 2002·Anti-cancer Drugs·Hitoshi YoshijiHiroshi Fukui
Sep 19, 2002·Cancer·Snehal G PatelDennis H Kraus
Nov 30, 2002·Oral Oncology·Phillip K PellitteriAlessandra Rinaldo
Jun 5, 2003·Current Opinion in Oncology·Erich M Sturgis, Bryan O Potter
Aug 15, 2003·Surgical Oncology Clinics of North America·Bryan O Potter, Erich M Sturgis
Apr 6, 2004·CA: a Cancer Journal for Clinicians·Janice N Cormier, Raphael E Pollock
May 15, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Vinay RajaJack B Alperin
Jun 3, 2004·Annals of Surgical Oncology·Brandon G BentzDennis Kraus
May 1, 2007·Oral Oncology·Sven JasnauUNKNOWN Cooperative Osteosarcoma Study Group COSS

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Citations

Nov 28, 2013·Journal of Cancer Research and Clinical Oncology·Thomas MückeAnastasios Kanatas
Sep 26, 2015·European Annals of Otorhinolaryngology, Head and Neck Diseases·C Galy-Bernadoy, R Garrel
Feb 26, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Anja SchützAndreas Kolk
Oct 16, 2010·Oral Oncology·Remco de BreeC René Leemans
Mar 25, 2014·European Annals of Otorhinolaryngology, Head and Neck Diseases·J BarosaE Monteiro
May 8, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Eelco de BreeRemco de Bree
Oct 28, 2011·Brazilian Oral Research·Rafael Morales VadilloJanet Ofelia Guevara Canales
Feb 1, 2017·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Ben Tudor-GreenPeter A Brennan
Jan 23, 2017·Oral Oncology·Leandros-Vassilios VassiliouNicholas Kalavrezos
Sep 27, 2014·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Amy E ChangRobin L Jones
Jul 22, 2016·Rare Tumors·Lucas K VitzthumRobert L Foote
Apr 18, 2019·Journal of Surgical Oncology·Ivana PetrovicJatin P Shah
Mar 19, 2020·Acta Oto-laryngologica·Mathilde AallingTherese Ovesen
May 19, 2012·Journal of Surgical Oncology·Valerie A SmithEric J Lentsch
Nov 30, 2019·The Journal of Laryngology and Otology·L HarrisonN Beasley
Aug 11, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·HeeJung KimMan Ki Chung
Feb 28, 2020·International Journal of Environmental Research and Public Health·Khrystyna ZhurakivskaLuigi Laino
Feb 16, 2021·Oral and Maxillofacial Surgery·Alejandro YanzonMarcelo Figari
Jul 9, 2020·The British Journal of Oral & Maxillofacial Surgery·N Kalavrezos, D Sinha
Jun 15, 2021·Head & Neck·Rohan SawhneyRichard Chan Woo Park
Apr 9, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D MattavelliM Fiore
Aug 11, 2021·BMJ Case Reports·Ramani ThiagarajahRajesh Kumar Muniandy
Aug 28, 2021·Annals of the Royal College of Surgeons of England·S KotechaT Cosker
Nov 14, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Johan H RoosTaru T Ilmarinen

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