Outcome measures in acute gout: a systematic literature review

The Journal of Rheumatology
Nicola DalbethWilliam J Taylor

Abstract

Five core domains have been endorsed by Outcome Measures in Rheumatology (OMERACT) for acute gout: pain, joint swelling, joint tenderness, patient global assessment, and activity limitation. We evaluated instruments for these domains according to the OMERACT filter: truth, feasibility, and discrimination. A systematic search strategy for instruments used to measure the acute gout core domains was formulated. For each method, articles were assessed by 2 reviewers to summarize information according to the specific components of the OMERACT filter. Seventy-seven articles and abstracts met the inclusion criteria. Pain was most frequently reported (76 studies, 20 instruments). The pain instruments used most often were 100 mm visual analog scale (VAS) and 5-point Likert scale. Both methods have high feasibility, face and content validity, and within- and between-group discrimination. Four-point Likert scales assessing index joint swelling and tenderness have been used in numerous acute gout studies; these instruments are feasible, with high face and content validity, and show within- and between-group discrimination. Five-point Patient Global Assessment of Response to Treatment (PGART) scales are feasible and valid, and show within- ...Continue Reading

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Citations

Feb 27, 2015·Biochemistry. Biokhimii︠a︡·I V AstrakhantsevaS A Nedospasov
Sep 9, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·C B TerweeL B Mokkink
Dec 18, 2013·The Journal of Rheumatology·Jasvinder A SinghN Lawrence Edwards
Jan 17, 2014·The Journal of Rheumatology·William J TaylorJasvinder A Singh
Jun 7, 2017·International Journal of Rheumatic Diseases·Binoy J Paul, Reeta James
Nov 17, 2016·Orthopaedic Nursing·Mariann Harding
Sep 29, 2020·Journal of Clinical Epidemiology·Karen L HughesPaula R Williamson
Feb 25, 2018·Biochemical and Biophysical Research Communications·Yang LiuYongtong Cao
Aug 27, 2021·The Cochrane Database of Systematic Reviews·Bayden J McKenzieRachelle Buchbinder

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