Outcome of 110 basal cell carcinomas of the eyelid treated with frozen section-controlled excision: mean follow-up over 5 years

European Journal of Ophthalmology
Antonio Giordano RestiFrancesco Bandello

Abstract

To analyze the outcome and risk factors of recurrence in patients with basal cell carcinomas (BCCs) of the eyelid treated by en face frozen section-controlled (FSC) excision with a mean follow-up over 5 years. This was a retrospective series of 108 patients with 110 biopsy-proven eyelid BCCs. All lesions were excised with 2 mm margins clinically free from neoplasia at clinical examination. For each tumor, en face frozen section examination of surgical margins was employed for the histologic confirmation before the reconstruction. Subsequently, all margins were submitted for permanent paraffin sections. Of 110 malignancies, 80.9% represented primary carcinomas and 19.1% secondary ones. The overall recurrence rate was 1.8%, with a mean follow-up of 72.4 months (range 30-167). The mean time between the excision of the lesion and the diagnosis of the recurrence was 24 months (range 20-28). No recurrences were observed in 62 tumors followed up for at least 5 years. Secondary BCCs were associated with a higher recurrence rate compared with primary BCCs (4.8% and 1.1%, respectively, p = 0.262). The FSC excision of eyelid BCCs yields recurrence rates comparable to those of Mohs micrographic surgery at 5-year follow-up. Intraoperative m...Continue Reading

References

Jun 1, 1979·American Journal of Ophthalmology·J Chalfin, A M Putterman
Dec 1, 1985·The Journal of Dermatologic Surgery and Oncology·P RobinsD Rigel
Jun 1, 1981·American Journal of Ophthalmology·M T DoxanasC E Iliff
Nov 20, 2002·Ophthalmic Plastic and Reconstructive Surgery·Vincent A WongTimothy J Sullivan
Feb 24, 2004·The British Journal of Ophthalmology·J D HsuanC Collins
Apr 2, 2005·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·J AllaliG Renard
Apr 6, 2005·Ophthalmology·Igal LeibovitchDinesh Selva
Nov 25, 2005·The New England Journal of Medicine·Adam I RubinDésirée Ratner
Aug 1, 2006·American Journal of Ophthalmology·Arie Y NemetRoss Benger
Feb 27, 2007·Indian Journal of Ophthalmology·K TaherianP L Atkinson
Mar 30, 2010·International Ophthalmology Clinics·Geva E MannorDavid Barnette
Mar 13, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jordan B Slutsky, Evan C Jones

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Citations

Mar 19, 2019·The Journal of Craniofacial Surgery·Orapan AryasitNimastika Hajeewaming
Nov 27, 2019·The Journal of Dermatological Treatment·Kevin PhanAnousha Yazdabadi
Jul 14, 2019·The Journal of Craniofacial Surgery·Orapan AryasitNimastika Hajeewaming
Jul 28, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Bulent YaziciDale R Meyer

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Methods Mentioned

BETA
biopsy
surgical resection

Software Mentioned

SPSS Statistics

Related Concepts

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Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

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