Outcome of colonic surgery in elderly patients with colon cancer.

Journal of Oncology
E HermansK Bosscha

Abstract

Introduction. Colonic cancer is one of the most commonly diagnosed malignancies and most often occurs in patients aged 65 years or older. Aim. To evaluate the outcome of colonic surgery in the elderly in our hospital and to compare five-year survival rates between the younger and elderly patients. Methods. 207 consecutive patients underwent surgery for colon cancer. Patients were separated in patients younger than 75 and older than 75 years. Results. Elderly patients presented significantly more (P < .05) as a surgical emergency, had a longer duration of admission and were more often admitted to the ICU (P < .01). Also, elderly patients had significant more co-morbidities, especially cardiovascular pathology (P < .01). Post-operative complications were seen more often in the elderly, although no significant difference was seen in anastomotic leakage. The five-year survival rate in the younger group was 62% compared with 36% in the elderly (P < .05). DFS was 61% in the younger patients compared with 32% in the elderly (P < .05). Conclusion. Curative resection of colonic carcinoma in the elderly is well tolerated and age alone should not be an indication for less aggressive therapy. However, the type and number of co-morbidities ...Continue Reading

References

Nov 11, 1991·Diseases of the Colon and Rectum·W E WiseW R Stewart
May 1, 1988·The British Journal of Surgery·T T Irvin
Jul 1, 1985·American Journal of Surgery·A G GreenburgD Pridham
Nov 1, 1985·Age and Ageing·T Wobbes
Mar 1, 1995·The British Journal of Surgery·N A ScottR D Kingston
Feb 1, 1993·Diseases of the Colon and Rectum·S D FitzgeraldA M Vernava
Mar 26, 1998·Diseases of the Colon and Rectum·V VioliA Peracchia
Feb 1, 2000·Journal of the History of the Behavioral Sciences·I Verstegen
Mar 31, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M F De MarcoJ W Coebergh
Jul 13, 2000·The European Journal of Surgery = Acta Chirurgica·J T MäkeläS Laitinen
Oct 2, 2001·CA: a Cancer Journal for Clinicians·R T GreenleeM Thun
May 4, 2004·The British Journal of Surgery·C S McArdle, D J Hole
Mar 22, 2005·The British Journal of Surgery·V E P P LemmensJ W W Coebergh
Aug 11, 2005·Alimentary Pharmacology & Therapeutics·A M BouvierJ Faivre
Oct 2, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J FaivreA M Bouvier

❮ Previous
Next ❯

Citations

May 17, 2011·International Journal of Colorectal Disease·Yanxin AnQingchuan Zhao
Jan 9, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Shamfa C JosephSteven Osiro
Aug 10, 2011·American Journal of Surgery·Ravikrishna Mamidanna, Omar Faiz
Nov 12, 2016·Aging Clinical and Experimental Research·Carlo BoselliNicola Avenia
Jul 30, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Beatriz Korc-GrodzickiRiccardo A Audisio
Oct 11, 2016·World Journal of Gastrointestinal Surgery·Antonio BiondiFrancesco Basile
Jul 13, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D PapamichaelM Aapro
Aug 18, 2020·Annals of the Royal College of Surgeons of England·J FranklynS Smolarek
Aug 11, 2020·Journal of the Chinese Medical Association : JCMA·Chih-Sheng HuangShung-Haur Yang
Sep 27, 2018·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Ilaria FrancoRiccardo Memeo
Jun 1, 2018·Journal of Oncology·Tadesse Melaku AbegazBegashaw Melaku Gebresillassie
Feb 6, 2020·Scandinavian Journal of Gastroenterology·Peilin ZhengZhikang Chen
Oct 23, 2020·ANZ Journal of Surgery·Hyerin ParkRupert Hodder
May 16, 2021·The Journal of International Medical Research·Shuanhu WangWenbin Wang

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.