Outcome of duodenum-preserving resection of the head of the pancreas for intraductal papillary-mucinous neoplasm

Digestive Surgery
Satoshi HiranoHiroyuki Katoh

Abstract

The standard surgical procedure for intraductal papillary-mucinous neoplasm of the pancreatic head is pylorus-preserving pancreatoduodenectomy. A less extensive resection may be justified because most intraductal papillary-mucinous neoplasms are benign or of low-grade malignancy. The outcome of duodenum-preserving pancreatic head resection with preservation of the main bile duct was evaluated retrospectively in 13 patients with a branch-type intraductal papillary-mucinous neoplasm in the head of the pancreas and with a median (range) follow-up of 60.0 (0.3-99.5) months. Post-operative complications included anastomotic leakage (n=3), bile duct perforation (n=1), intra-abdominal bleeding (n=3), delayed gastric emptying (n=2) and death (n=2). All the resection margins were clear of tumour on histological examination. Ten of 11 patients maintained over 90% of their pre-operative body weight. Glucose tolerance improved in 4 of 11 evaluable patients, was unchanged in 6 and worsened in 1 patient. Biliary scintigraphy showed that bile flow was delayed compared with that before surgery (8.8 +/- 1.1 vs. 19.6 +/- 4.6 min; p = 0.03). Neither recurrence nor metastasis was observed. The results of duodenum-preserving pancreatic head resecti...Continue Reading

Citations

Jul 14, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hans G BegerBertram Poch
Nov 29, 2007·Annals of Surgery·Akimasa Nakao, Laureano Fernández-Cruz
Apr 20, 2014·International Journal of Surgery·H G BegerC Vasilescu
Apr 9, 2013·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Takahiro TsuchikawaMasaki Miyamoto
Nov 4, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hans G BegerBettina M Rau
Nov 3, 2009·Journal of Hepato-biliary-pancreatic Sciences·Akimasa NakaoSuguru Yamada
Aug 10, 2010·Journal of Hepato-biliary-pancreatic Sciences·Sergio PedrazzoliCosimo Sperti
Feb 19, 2015·World Journal of Surgery·H G BegerM H Schoenberg
Mar 4, 2015·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Hans G BegerBertram Poch
Mar 3, 2018·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Yu JiangBai-Yong Shen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.