PMID: 11912403Mar 26, 2002Paper

Outcome of in vitro fertilization and intracytoplasmic injection of epididymal and testicular sperm obtained from patients with obstructive and nonobstructive azoospermia

The Journal of Urology
Fabio Firmback PasqualottoEdson Borges

Abstract

We assessed fertilization, pregnancy and miscarriage rates in patients with obstructive and nonobstructive azoospermia who underwent intracytoplasmic sperm injection. From June 1996 to March 2000, 166 consecutive patients (198 intracytoplasmic sperm injection cycles) with azoospermia were studied. Of these 198 cycles 68 were performed due to nonobstructive azoospermia using testicular spermatozoa and 130 were performed due to obstructive azoospermia using epididymal spermatozoa. The normal (2 pronuclei) and abnormal (1 plus 3 pronuclei) fertilization rates for obstructive and nonobstructive azoospermia were 60.5% and 16.6%, and 54% and 16.4%, respectively (p >0.05). The pregnancy rate per cycle, pregnancy rate per patient and abortion rate were 30%, 39.8% and 28% for obstructive azoospermia, and 22%, 28.3% and 40% for nonobstructive azoospermia (p <0.05). The normal and abnormal fertilization rates were 58.7% and 21.4% for percutaneous epididymal sperm aspiration (PESA), 62.3% and 10.4% for PESA plus testicular sperm aspiration (TESA), and 57.3% and 14.5% for TESA, respectively (p >0.05). The pregnancy rate per cycle, pregnancy rate per patient and abortion rate were 34.6%, 54.5% and 11.1% for PESA, 37.5%, 37.5% and 33.3% for P...Continue Reading

References

Sep 1, 1985·Journal of in Vitro Fertilization and Embryo Transfer : IVF·P D Temple-SmithD M de Kretser
Nov 13, 1993·Lancet·R SchoysmanD Schoysman
Nov 18, 1997·Human Reproduction·R T MansourM A Aboulghar
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Sep 16, 2000·Molecular and Cellular Endocrinology·Z P Nagy

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Citations

Jan 28, 2005·Journal of Assisted Reproduction and Genetics·James D M NicopoullosPaula A Almeida
Dec 7, 2005·Journal of Assisted Reproduction and Genetics·Bin WuTimothy J Gelety
Mar 8, 2005·Fertility and Sterility·Fábio F PasqualottoEdson Borges
Feb 20, 2004·Urology·Karen Elizabeth BoyleJonathan P Jarow
Sep 24, 2005·Reproductive Biomedicine Online·Moshe WaldCraig S Niederberger
May 22, 2003·Best Practice & Research. Clinical Obstetrics & Gynaecology·E IammarroneJ G Grudzinskas
May 20, 2008·Journal of Experimental & Clinical Assisted Reproduction·Laszlo Nanassy, Douglas T Carrell
Nov 29, 2011·Asian Journal of Andrology·Natalya A Lopushnyan, Thomas J Walsh
Jun 27, 2015·Systems Biology in Reproductive Medicine·Yong-Seog ParkJu Tae Seo
Oct 15, 2010·Systems Biology in Reproductive Medicine·Xiaojin HeLin Cong
Feb 6, 2004·Revista do Hospital das Clínicas·Fabio Firmbach PasqualottoAnthony Joseph Thomas
Nov 16, 2004·Revista do Hospital das Clínicas·Fábio Firmbach PasqualottoSami Arap
May 9, 2008·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Fabio Firmbach Pasqualotto, Edson Borges
Jan 21, 2009·The Journal of Urology·Nagwa Roshdy, Taymour Mostafa
Apr 11, 2003·The Journal of Urology·Fabio F PasqualottoEdson Borges
Sep 27, 2006·Birth Defects Research. Part A, Clinical and Molecular Teratology·Daniel Doherty, David B Shurtleff
Jan 30, 2008·Nature Clinical Practice. Urology·Justin S Han, Robert E Brannigan
Feb 24, 2006·Urologia Internationalis·Fabio Firmbach PasqualottoAntônio Marmo Lucon
Feb 4, 2010·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Luciana - Semião-FranciscoEdson Borges

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