PMID: 16505754Mar 1, 2006Paper

Outcome of infants with celiac disease

Gastroentérologie Clinique Et Biologique
Jean-Jacques BaudonJacques Cosnes

Abstract

Determine the proportion of infants whose celiac disease (CD) was confirmed in childhood and evaluate their prognosis in adulthood. The diagnosis of CD was established between 1971 and 1982 in 84 infants based on intestinal biopsy data; a gluten-free diet was prescribed and the cohort followed prospectively. Thirty-six infants were followed less than 5 years. A second biopsy was performed in 25. Mucosa had healed in 13 and remained atrophic in 12. Three children developed partial villous atrophy between 6 and 12 years of age in spite of the gluten-free diet. Forty-five patients underwent a gluten challenge between 5 and 10 years of age: in 41 histological lesions relapsed, in two mucosa remained normal and clinical and immunological relapse developed in two. Among those 45 patients, 18 were examined after 18 years follow-up: the exclusion diet was resumed in four, overt clinical relapse developed in four and four experienced intermittent gastrointestinal disorders. All biopsies performed during a period of normal diet showed villous atrophy (except in one patient) without correlation with clinical symptoms. The diagnosis of celiac disease in infants was confirmed in nearly all cases in childhood. When they reached adulthood, th...Continue Reading

References

Aug 1, 1991·Archives of Disease in Childhood·A Bürgin-WolffC Reymond-Berthet
Nov 1, 1989·Archives of Disease in Childhood·M MäkiJ K Visakorpi
May 1, 1989·Journal of Pediatric Gastroenterology and Nutrition·M MayerG Pansa
Jul 1, 1987·Journal of Pediatric Gastroenterology and Nutrition·A KapuscinskaT Rossi
Aug 1, 1988·Archives of Disease in Childhood·P J KumarR Halliday
Jul 1, 1987·Archives of Disease in Childhood·J ColacoB McNicholl
Aug 1, 1971·Archives of Disease in Childhood·W F Young, E M Pringle
Jul 6, 1968·British Medical Journal·P E MortimerC C Booth
Sep 1, 1994·Gut·P CollinA Pasternack
Mar 1, 1994·Archives of Disease in Childhood·M T BardellaP A Bianchi
Apr 1, 1996·The American Journal of Gastroenterology·C CiacciG Mazzacca
May 1, 1996·Acta Paediatrica. Supplement·G K Holmes

❮ Previous
Next ❯

Citations

Feb 21, 2009·World Journal of Gastroenterology : WJG·Eric V MariettaJoseph A Murray

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Alimentary Pharmacology & Therapeutics
P G Hill, G K T Holmes
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
J Schmitz, H Garnier-Lengliné
The New England Journal of Medicine
Peter H R Green, Christophe Cellier
© 2021 Meta ULC. All rights reserved