Outcome of infants with prenatally diagnosed congenital heart disease delivered outside specialist paediatric cardiac centres

Archives of Disease in Childhood. Fetal and Neonatal Edition
Katherine AnagnostouWilf Kelsall


To determine the outcome of neonates with a suspected antenatal diagnosis of congenital heart disease (CHD) who were delivered away from a paediatric cardiothoracic centre and were initially managed in a level 3 Neonatal Intensive Care Unit. An 18-year ongoing study conducted in a single institution. Between 1992 and 2009, 143 fetuses with suspected CHD were identified, and 124 babies were delivered locally. 13 babies with a normal postnatal echocardiogram and six with isolated arrhythmias were excluded from the study. Structural CHD was confirmed in 105 infants; of these, 94 (90%) survived the neonatal period. Of the 11 neonatal deaths, only four of these infants underwent surgery; most had additional risk factors including: prematurity, very low birth weight, and genetic and other structural congenital anomalies. This study demonstrates that appropriately selected infants with antenatally diagnosed CHD can be safely delivered and initially managed in a non-cardiac centre during their neonatal period. Deliveries need to be carefully planned with close collaboration among neonatologists, obstetricians, paediatric cardiologists, mid-wives and parents.


Dec 18, 2012·Archives of Disease in Childhood. Fetal and Neonatal Edition·Martin P Ward Platt
Dec 12, 2013·European Journal of Pediatrics·Neelam GuptaNeil Patel
May 31, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·C A WalshF M McAuliffe
Feb 16, 2016·Clinics in Perinatology·Laura SanapoMary T Donofrio
Feb 6, 2016·Yonsei Medical Journal·Shigeki KoshidaKentaro Takahashi
Jun 8, 2013·Seminars in Fetal & Neonatal Medicine·Alice WielandnerVanessa Berger-Kulemann
May 27, 2016·Cardiology in the Young·Myriam BensemlaliDamien Bonnet
Jun 8, 2017·Cardiology in the Young·Hannah C JacobA Wilfred Kelsall
Apr 26, 2014·Circulation·Mary T DonofrioAmerican Heart Association Adults With Congenital Heart Disease Joint Committee of the Council on Cardiovascular Disease in
Jun 17, 2014·Journal of Cardiovascular Medicine·Vlasta Fesslova'Fetal Study Group of Italian Society of Pediatric Cardiology
Aug 29, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Rebekka LytzenLars Søndergaard
Jul 17, 2017·Pediatric Cardiology·Michael F SwartzGeorge M Alfieris

Related Concepts

Congenital Heart Defects
Intensive Care Units, Neonatal
Antenatal Screening Procedures
Outcomes Research
Obstetric Delivery
Congenital Abnormality
Intensive Care Units, Neonatal

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