PMID: 11321655Apr 26, 2001Paper

Outcome of ipsilateral treatment for patients with metastases to neck nodes of unknown origin

Acta Oncologica
S FrieslandJ O Fernberg

Abstract

It is not uncommon for head and neck cancer patients to present with neck node metastases. Standard treatment for patients in whom no primary tumor is found include surgery and radiotherapy but there is still controversy about the type and extent of treatment. A retrospective review was carried out on 51 consecutive patients with cervical lymph node metastases of unknown origin, treated between 1980 and 1994 at Radiumhemmet, Karolinska Hospital. All patients received radiotherapy to the ipsilateral neck and the corresponding mucosa and surgery was performed in 55% of cases. The 5-year overall survival rate was 41%. A primary tumor was later found in 6 cases (12%). Two cases of cancer were detected after 5 years and classified as 'second primaries'. Results from this small retrospective material have to be interpreted with caution but indicate that limited, ipsilateral radiotherapy to mucosa and lymph nodes combined with surgery, when possible, may be justified.

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Citations

Apr 19, 2011·International Journal of Radiation Oncology, Biology, Physics·Hugo VilleneuvePhuc Felix Nguyen-Tan
Nov 7, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A LigeyP Maingon
Aug 25, 2007·International Journal of Radiation Oncology, Biology, Physics·Debora BeldìMarco Krengli
Jan 27, 2015·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Young Mi SeolSoo Geun Wang
Aug 30, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Chun-Chi HuangYuh-Shyang Chen
May 18, 2007·Annals of Surgical Oncology·Paolo Boscolo-RizzoMaria Cristina Da Mosto

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