Outcome of liver transplantation for hepatitis B in the United States

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
W Ray KimE Rolland Dickson

Abstract

Important innovations, such as hepatitis B immune globulin (HBIG) and lamivudine, have been introduced to the care of patients undergoing liver transplantation (OLT) for viral hepatitis B (HBV) (over the last 15 years). We analyzed survival of OLT recipients with HBV in the United States to examine the effect of these innovations. A retrospective analysis was conducted based on data collected prospectively by the United Network for Organ Sharing in all adult (older than 18) patients undergoing primary OLT in the United States between 1987 and 2002. OLT recipients with HBV were identified by the principal diagnosis of acute or chronic HBV or positive results on HBV markers. Patients were divided into Era 1 (1987-1991), Era 2 (1992-1996), and Era 3 (1997-2002). Era 1 consisted of 6,708 patients (675 with HBV), Era 2 consisted of 13,995 patients (1,005 with HBV), and Era 3 consisted of 20,730 patients (1,723 with HBV). More recent patients were older and had less advanced liver disease and shorter ischemic time. The survival of patients with HBV was significantly better for Era 2 than for Era 1 (P <.01) and for Era 3 than for Era 2 (P <.01). There was no difference in survival between patients with HBV and all other diagnoses for ...Continue Reading

References

Jan 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S E DaviesR Williams
Aug 29, 1987·Lancet·M RizzettoF Milazzo
Jan 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D H Van ThielT E Starzl
Dec 21, 1995·The New England Journal of Medicine·J L DienstagM Rubin
Feb 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D SamuelP Gentilini
Dec 16, 1993·The New England Journal of Medicine·D SamuelH Bismuth
Dec 1, 1996·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N A TerraultT L Wright
Jan 1, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·B M HoE B Keeffe
Apr 27, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R PerrilloN Brown
Jun 28, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R PerrilloA Murray
Jul 29, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·P W AngusH Harley
Nov 21, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·S H HanP Martin
Feb 15, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R P PerrilloUNKNOWN Lamivudine North American Transplant Group
Jun 30, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·E K TeoUNKNOWN HBV-OLT Study Group
May 1, 2002·Annals of Surgery·Dean M AnselmoRonald W Busuttil
May 11, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Robert J FontanaUNKNOWN National Institutes of Health Hepatitis B Virus Orthotopic Liver Transplantation Study Group
May 25, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Thomas SteinmüllerPeter Neuhaus
Oct 4, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Norah A Terrault

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Citations

Oct 3, 2006·Journal of Hepato-biliary-pancreatic Surgery·Yasuhiko Sugawara, Masatoshi Makuuchi
Dec 19, 2008·Nature Clinical Practice. Gastroenterology & Hepatology·Bulent Degertekin, Anna S Lok
Nov 16, 2005·Transplantation·Daniel Seehofer, Thomas Berg
Mar 21, 2009·Transplantation·Susanne BeckebaumVito R Cicinnati
Aug 12, 2009·Transplantation·Nyingi M Kemmer, Guy W Neff
May 14, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Pavani Naini ReddySuphamai Bunnapradist
May 27, 2009·World Journal of Gastroenterology : WJG·Li JiangLu-Nan Yan
May 1, 2010·Gut and Liver·Deok-Bog Moon, Sung-Gyu Lee
Mar 14, 2013·Hepatitis Monthly·Seyed Mohsen DehghaniSeyed Ali Malek-Hosseini
Oct 19, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Bruce Y Tung, Kris V Kowdley
Dec 3, 2014·Clinics in Liver Disease·Ming-Ming Xu, Robert S Brown
Apr 26, 2014·Expert Review of Gastroenterology & Hepatology·Fa-Ling WuMing-Hua Zheng
Apr 29, 2014·Transplantation Proceedings·Y SirivatanauksornS Asavakarn
Jul 3, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Kimberly A FordeK Rajender Reddy
Aug 3, 2013·Clinics in Liver Disease·Bruno Roche, Didier Samuel
May 1, 2012·Clinics in Liver Disease·Alyson N Fox, Robert S Brown
Jul 20, 2010·Clinics in Liver Disease·Hui-Hui Tan, Paul Martin
Oct 16, 2009·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Franco FilipponiMauro Salizzoni
Jun 24, 2008·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Stephen BarclayWilliam Carman
Jan 22, 2008·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Stephen BarclayWilliam Cameron
Nov 6, 2007·Clinics in Liver Disease·Ilan S WeisbergSamuel H Sigal
Jul 7, 2007·Archives of Medical Research·Marco Antonio Olivera-Martínez, Juan F Gallegos-Orozco
Oct 12, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Tae Hoon LeeW Ray Kim
Oct 21, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Bijan EghtesadThomas E Starzl
Sep 24, 2005·Pediatric Transplantation·Nanda Kerkar
Nov 13, 2009·Journal of Digestive Diseases·Zhi Feng XiDe Kai Qiu
Apr 29, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·W Ray Kim
Apr 29, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Marion G Peters
Sep 1, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Charles D Howell
May 8, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Rami MoucariFrançois Durand
Nov 21, 2007·Journal of Viral Hepatitis·Carla S Coffin, Norah A Terrault
May 12, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Y FutagawaD W Gjertson
Aug 18, 2006·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J DumortierO Boillot
Sep 20, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Marina Berenguer
Feb 5, 2009·Clinical Transplantation·Maria L YatacoJustin Nguyen
Apr 14, 2006·Alimentary Pharmacology & Therapeutics·D Mutimer
Sep 26, 2008·Reviews in Medical Virology·Susanne BeckebaumVito R Cicinnati
Apr 12, 2007·Clinical Transplantation·Kinan RifaiHans L Tillmann

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