Outcome of myelomeningocoele repair in sub-Saharan Africa: the Nigerian experience

Acta neurochirurgica
O E Idowu, R A Apemiye

Abstract

Early repair of myelomeningocoele (MM) is associated with decreased morbidity and mortality. In sub-Saharan Africa, the peculiar harsh economic and social realities make late presentation, malnutrition and sepsis at presentation prevalent. As these factors may affect surgical repair, the aim of this study was to review the outcome of repair of MM in this peculiar patient population. A prospective study of patients with MM who presented at the Lagos State University Teaching Hospital, Lagos, Nigeria over a 12 month period was studied. Follow up ranged from 8 weeks to 1 year. Five patients died while awaiting surgery. Thirty-six patients, 24 males and 12 female infants with MM were operated on during the study period. Majority of the patients were operated on or after the seventh day of life. The median age at surgery was 11th day of life (range second day-2 years). The mean surface area of the myelomeningocoele was 26.4 cm(2) (range 12.6-62.9 cm(2)). The post-operative morbidity and mortality was five and one, respectively. Intracranial sepsis is the main cause of death in MM patients who are not operated on time. The patients we are seeing are probably those that survived to present at the hospital; by that time primary closure...Continue Reading

References

Mar 1, 1985·Plastic and Reconstructive Surgery·E A Luce, J Walsh
Jan 1, 1983·Child's Brain·I R MunroC G Lauritzen
Oct 5, 2001·British Journal of Plastic Surgery·O LapidA Cohen
Nov 7, 2002·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M F OzverenI Akdemir
Jul 16, 2003·British Journal of Plastic Surgery·Nedim SarifakiogluGürcan Aslan
Feb 1, 1964·Archives of Disease in Childhood·K M LAURENCE

❮ Previous
Next ❯

Citations

Jul 28, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Olufemi E Idowu, Stephen O Oyeleke
Feb 3, 2011·Journal of Neurosurgery. Pediatrics·Benjamin C WarfAbhaya V Kulkarni
Sep 21, 2010·World Neurosurgery·Andrea Sylvia WinklerUNKNOWN East African Neurosurgical Research Collaboration
Oct 4, 2016·Journal of Neurosciences in Rural Practice·Taopheeq Bamidele Rabiu, Edward Oluwole Komolafe
Oct 14, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Edward O KomolafeMuhammad I Abdullahi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.