PMID: 3321921Jan 1, 1987Paper

Outcome of patients with diabetic nephropathy after kidney transplantation

Acta Medica Scandinavica
A EkstrandJ Ahonen

Abstract

During the period 1973-1983, 1,014 patients with end stage renal failure received a kidney graft at the Helsinki University Central Hospital. As a consequence of diabetic nephropathy, 163 of them (16%) developed renal failure. Ten diabetic (6%) and 72 non-diabetic (9%) patients received grafts from a living donor. One-year patient survival did not differ between diabetic and non-diabetic patients (76% and 79%, respectively). From the second post-transplant year onwards patient survival was worse in diabetic than in non-diabetic patients. The two groups did not differ with respect to graft survival. Sixty-two diabetic patients (38%) died during the follow-up period, with myocardial infarction as the most common cause of death (31%), followed by infection (15%) and cerebral stroke (13%). Seven myocardial infarctions out of 19 occurred within three months of transplantation. However, significantly more fatal and non-fatal myocardial infarctions were observed in post-transplant patients who had returned to dialysis therapy than in patients with a functioning kidney graft. Blindness did not influence the outcome of transplantation. Nor did the transplantation significantly affect the course of this diabetic complication. In conclusi...Continue Reading

References

Oct 1, 1979·Annals of Surgery·J S NajarianB G Sommer
Jan 1, 1985·Diabetic Medicine : a Journal of the British Diabetic Association·P J Watkins
Feb 1, 1985·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·P S ParfreyR D Guttmann
Feb 1, 1983·The Journal of Urology·A I SagalowskyP C Peters

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