Outcome of patients with right heart thrombi: the Right Heart Thrombi European Registry

The European Respiratory Journal
Marcin KoćRiHTER Investigators

Abstract

Our aim was the assessment of the prognostic significance of right heart thrombi (RiHT) and their characteristics in pulmonary embolism in relation to established prognostic factors.138 patients (69 females) aged (mean±sd) 62±19 years with RiHT were included into a multicenter registry. A control group of 276 patients without RiHT was created by propensity scoring from a cohort of 963 contemporary patients. The primary end-point was 30-day pulmonary embolism-related mortality; the secondary end-point included 30-day all-cause mortality. In RiHT patients, pulmonary embolism mortality was higher in 31 patients with systolic blood pressure <90 mmHg than in 107 normotensives (42% versus 12%, p=0.0002) and was higher in the 83 normotensives with right ventricular dysfunction (RVD) than in the 24 normotensives without RVD (16% versus 0%, p=0.038). In multivariable analysis the simplified Pulmonary Embolism Severity Index predicted mortality (hazard ratio 2.43, 95% CI 1.58-3.73; p<0.0001), while RiHT characteristics did not. Patients with RiHT had higher pulmonary embolism mortality than controls (19% versus 8%, p=0.003), especially normotensive patients with RVD (16% versus 7%, p=0.02).30-day mortality in patients with RiHT is relate...Continue Reading

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Citations

Dec 25, 2016·The American Journal of Medicine·Deisy BarriosUNKNOWN Registro Informatizado de la Enfermedad TromboEmbólica Investigators
Mar 2, 2016·The European Respiratory Journal·David Jiménez, Roger D Yusen
Nov 2, 2016·The European Respiratory Journal·Deisy BarriosUNKNOWN RIETE investigators
May 17, 2019·Clinical Medicine : Journal of the Royal College of Physicians of London·Luke Howard
Jul 14, 2019·Journal of Thrombosis and Haemostasis : JTH·Noémie KraaijpoelGrégoire Le Gal
Aug 24, 2019·Heart·Noura M DabbousehPaul Anthony Bergl
Aug 3, 2017·Cardiology in Review·Tanya DuttaWilbert S Aronow
Jun 20, 2020·BMJ Case Reports·Sara MontemeraniGiovanni Iannelli
May 5, 2017·Case Reports in Cardiology·João PortuguêsAntónio Lourenço
Oct 17, 2017·Annals of Vascular Diseases·Ikuo Fukuda, Kazuyuki Daitoku
Sep 19, 2019·BioMed Research International·Katarzyna Ptaszynska-KopczynskaBozena Sobkowicz
Feb 20, 2020·American Journal of Respiratory and Critical Care Medicine·Alexander E ShermanRichard N Channick
Jul 28, 2020·Circulation Research·Jelena KornejRenate B Schnabel
Oct 31, 2018·Journal of Intensive Care Medicine·Marjan IslamJason Filopei
Mar 7, 2019·American Journal of Therapeutics·Antoniu Octavian PetrişCălin Pop
May 21, 2020·The European Respiratory Journal·Behnood BikdeliUNKNOWN Coordinator of the RIETE Registry: Manuel Monreal. RIETE Steering Committee Members:
Nov 18, 2020·The Journal of Critical Care Medicine·Enrico MerloGabriele Martelli
Feb 7, 2021·Seminars in Respiratory and Critical Care Medicine·Georgios A TriantafyllouParth Rali
Dec 29, 2020·Seminars in Thrombosis and Hemostasis·Nina D AnfinogenovaWladimir Y Ussov

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