PMID: 15352426Sep 9, 2004Paper

Outcome of patients with systemic lupus erythematosus in intensive care unit

Lupus
A H AlzeerE A Bamgboye

Abstract

The objective of the study was to identify the causes, outcome and prognosis of severe illness in patients with systemic lupus erythematosus (SLE) requiring intensive care unit (ICU) care in a University Hospital over a five-year period. The design was a cohort study. Forty-eight SLE patients requiring ICU management over a five-year period (January 1997-December 2001) were studied prospectively. Of 48 patients, 14 (29.2%) died, predominantly with multiorgan dysfunction syndrome (MODS). Patients whose APACHE II score was equal to or greater than 20 had higher mortality than those with APACHE score below 20 (60 versus 7.1%; and P < 0.01). All the 18 patients whose health status rated as 'good' survived, while 46.7% of 30 patients whose health rated as 'poor' died (P < 0.01). Patients who had thrombocytopenia associated with sepsis and/or disseminated intravascular coagulopathy (DIC) had the highest mortality (75%, five-year survival). In conclusion, SLE patients admitted to the ICU had a lower mortality rate than some of the previous reports. Patients with SLE with high APACHE score, > or =20, poor health status, thrombocytopenia and multiorgan dysfunction syndrome had poor prognosis in the ICU.

References

May 1, 1992·Annals of the Rheumatic Diseases·B GodeauJ R Le Gall
Oct 1, 1991·Seminars in Arthritis and Rheumatism·M J Seleznick, J F Fries
Jan 1, 1990·Indian Journal of Pathology & Microbiology·N JayaramS Sehgal
Feb 1, 1985·Seminars in Arthritis and Rheumatism·A M SegalC S White
Nov 1, 1987·Seminars in Arthritis and Rheumatism·B F Mandell
May 1, 1986·American Journal of Clinical Pathology·J L Myers, A A Katzenstein
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Jan 1, 1983·American Journal of Clinical Pathology·E A RobertsonA C Van Steirteghem
Apr 1, 1980·Journal of Comparative and Physiological Psychology·P ShizgalJ Yeomans
Nov 1, 1982·Arthritis and Rheumatism·E M TanR J Winchester
Mar 1, 1994·American Journal of Respiratory and Critical Care Medicine·G R BernardR Spragg
Jun 1, 1996·Critical Care Medicine·S M AnsellC Feldman
Apr 18, 2002·Annals of the Rheumatic Diseases·F M K WilliamsR M Leach

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Citations

Feb 22, 2012·Medizinische Klinik, Intensivmedizin und Notfallmedizin·P LehmannM Fleck
Mar 10, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Xue XuShi Chen
Dec 22, 2015·Lupus Science & Medicine·Santiago Bernal-MacíasJuan-Manuel Anaya
Feb 1, 2007·Arthritis and Rheumatism·Mónica FernándezUNKNOWN LUMINA Study Group
Apr 3, 2008·Internal Medicine Journal·D MassassoF Joshua
Nov 19, 2010·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Javier A CavallascaGustavo G Nasswetter
Jun 30, 2012·Autoimmunity Reviews·Olga L QuinteroJuan-Manuel Anaya
Sep 15, 2016·Zeitschrift für Rheumatologie·L A RütterG Keyßer
Dec 17, 2008·Annals of the New York Academy of Sciences·Radan HuthOle Einar Tveito
Mar 17, 2018·BMC Public Health·Issam BennisMarleen Boelaert
Jun 27, 2006·Oncogene·M A AvilaJ Prieto
Oct 17, 2006·Oncogene·J H Reiling, D M Sabatini
Jan 27, 2018·Biomédica : revista del Instituto Nacional de Salud·Efren Avendaño-TamayoBerta Nelly Restrepo
Feb 7, 2019·Scientific Reports·Mathieu GouhierPhilippe Husson
Apr 19, 2019·Internal Medicine·George Umemoto, Hirokazu Furuya
Nov 22, 2013·Nature Communications·Robert C ReidDavid P Fairlie
Sep 16, 2010·American Journal of Physiology. Endocrinology and Metabolism·Caroline Bauchart-ThevretDouglas G Burrin
Sep 27, 2012·American Journal of Physiology. Endocrinology and Metabolism·Yvette C LuikingNicolaas E P Deutz
Apr 10, 2015·JPEN. Journal of Parenteral and Enteral Nutrition·Maria Emília Rabelo AndradeValbert Nascimento Cardoso
Aug 31, 2019·Zeitschrift für Rheumatologie·Gernot Keyßer
Dec 15, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Wolfgang LanghansMyrtha Arnold
Jul 12, 2019·Advances in Rheumatology·Maria Fernanda Alvarez BarrenecheMiguel Antonio Mesa Navas
Jul 30, 2020·Lupus·Ana Suárez-AvellanedaGabriel J Tobón

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