Outcome of photodynamic therapy in choroidal neovascularization due to pathologic myopia and related factors.

International Ophthalmology
Tugrul AltanSezin Ozdogan

Abstract

To evaluate the outcome of photodynamic therapy (PDT) and the factors influencing its outcome in patients with subfoveal choroidal neovascularization (CNV) due to pathologic myopia. Twenty-three eyes of 21 consecutive patients who received PDT for subfoveal CNV due to pathologic myopia and who were followed for >12 months were included in the study. The relationship between the factors that might affect the treatment outcome were evaluated. Mean age was 48.7 ± 16.0 years (23-74 years). Mean follow-up was 23.2 ± 7.7 months (15-41 months). Mean logMAR visual acuity was 0.85 ± 0.24 before treatment, 0.89 ± 0.37 at 12 months, and 0.92 ± 0.46 at the final visit. Mean logMAR visual acuity did not change significantly at 12 months or at the final visit (P = 0.47 and 0.36, respectively). The baseline visual acuity strongly correlated with the final visual acuity (P = 0.001). Age showed an inverse correlation with change in logMAR visual acuity at 12 months (P = 0.01). PDT prevented significant visual loss in eyes with subfoveal CNV due to pathologic myopia. Better initial visual acuity resulted in better final visual acuity. Younger age was correlated with better treatment outcome at 12 months.

References

Jan 1, 1988·Acta Ophthalmologica. Supplement·T Tokoro
Dec 1, 1984·Ophthalmology·M P AvilaC L Schepens
Aug 1, 1983·Ophthalmology·G R HamptonA C Bird
Mar 1, 1983·Archives of Ophthalmology·R D SperdutoM Rowland
Oct 1, 1993·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M R AngiC Bisantis
Mar 18, 2000·Archives of Ophthalmology·A Uemura, M A Thomas
Aug 25, 2001·The British Journal of Ophthalmology·J M Ruiz-Moreno, C de la Vega
Nov 14, 2002·American Journal of Ophthalmology·Yasuo Tano
Aug 4, 2004·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kengo HayashiManabu Mochizuki
Sep 6, 2005·American Journal of Ophthalmology·Ilse KrebsAlexandra Goll
Feb 9, 2006·The British Journal of Ophthalmology·A García-LayanaA Fernández-Hortelano
Apr 22, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ariko KojimaManabu Mochizuki

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Citations

Jul 6, 2014·The British Journal of Ophthalmology·Tien Y WongAdnan Tufail

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