Outcome of Pregnancy with Hemoglobinopathy in a Tertiary Care Center

Journal of Obstetrics and Gynaecology of India
Anahita Chauhan, Madhva Prasad


The objective was to observe the characteristics among pregnant patients with a diagnosed hemoglobinopathy and to study the obstetric and medical morbidity patterns during the antenatal and the perinatal periods in this group of patients. A prospective observational study was conducted in a tertiary care center. Sixty patients were studied in 11 months. Primigravidae (43.3%) formed the highest percentage of patients. β Thalassemia trait was the most common hemoglobinopathy, seen in 81.66% of study subjects. The hemoglobin value ranged from 5.7 to 13.0, with an average of 9.2 g/dl. Thyroid problems were the most common associated medical disorder. Though IUGR and placenta previa were common, there were no major obstetric problems. There were 57 live births and 1 fresh stillbirth. Two patients had spontaneous abortion for which uterine curettage was done. LSCS was the most common obstetric outcome. Patients with sickle-cell disease required more blood transfusion than those with beta-thalassemia trait. There were 2 maternal mortalities, and both the patients were the diagnosed cases of sickle-cell disease. While the perinatal outcomes among women with sickle-cell disease are poor, the outcomes in pregnant patients with beta-thala...Continue Reading


Oct 22, 2009·Hematology·Constantinos TsatalasEmmanouil Spanoudakis
Aug 6, 2010·Obstetrics and Gynecology Clinics of North America·Dennie T Rogers, Robert Molokie
Oct 19, 2011·Hemoglobin·Tuphan Kanti DolaiMalay Kumar Ghosh
Jun 14, 2012·Prenatal Diagnosis·A El-BeshlawyM Petrou
May 18, 2013·Archives of Gynecology and Obstetrics·Tharangrut HanprasertpongSavitree Pranpanus
Aug 21, 2013·Hemoglobin·Mayoor M DaigavaneTushar J Kar
Jan 16, 2014·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Asha BaxiBaxi Heena
Jun 4, 2014·European Journal of Haematology·Ersi VoskaridouEvangelos Terpos
Apr 30, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Walairat KemthongTheera Tongsong
Oct 20, 2015·Archives of Gynecology and Obstetrics·Chitrakan CharoenboonTheera Tongsong
Jan 23, 2017·Journal of Health, Population, and Nutrition·Gayatri DesaiDhiren Modi

Related Concepts

Anemia, Sickle Cell
Beta Thalassemia
Blood Transfusion
Fetal Growth Retardation
Pregnant Women
Thyroid Gland

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