Outcome of totally implantable venous-access port-related infections

Médecine et maladies infectieuses
M VidalO Lesens

Abstract

We aimed to study factors associated with the outcome of totally implantable venous-access port (TIVAP)-related infections. We conducted a prospective and observational cohort study of patients presenting with a solid tumor and TIVAP-related infection. We monitored 97 patients for 12weeks. The case fatality at 12weeks was high (54%). Factors associated with case fatality at week 12 included patients' underlying cancer (metastatic status, parenteral nutrition, home care). Infectious complications (local abscess, hematogenous metastases, infection recurrence, septic shock) were frequently observed (48%). The delay in TIVAP removal was the only variable significantly associated with complications (TIVAP removed more than a week after removal decision, P=0.001, or more than a week after onset of clinical symptoms, P=0.002). On the basis of IDSA guidelines, we also observed that 25% of patients whose TIVAP had been removed could have benefited from a conservative treatment. Infections occurring within a month of TIVAP implantation were significantly associated with a Staphylococcus aureus infection (P=0.008). Case fatality is high in this population of patients due to the poor status of patients. TIVAP should be promptly removed whe...Continue Reading

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Citations

Mar 30, 2018·Annals of Intensive Care·Marie LecronierUNKNOWN GrrrOH (Group for Research in Respiratory Intensive Care Onco-Hematology)
Mar 8, 2018·The Journal of Vascular Access·Fulvio PinelliMauro Pittiruti
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Sep 23, 2021·Langenbeck's Archives of Surgery·Tung-Cheng ChangKee-Thai Kiu

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