Outcome parameters in ankylosing spondylitis

Zeitschrift für Rheumatologie
H HaibelJ Sieper

Abstract

Ankylosing spondylitis (AS) is a frequent inflammatory rheumatic disease and prototype of the Spondyloarthitides (SpA). During the last years outcome parameters have been developed to evaluate different aspects of the disease. Among these are the Bath AS Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), Bath AS Metrology Index (BASMI), numeric rating scales for general pain, night pain, patients and physicians global assessment, as well as questionnaires to evaluate quality of life as the short Form (SF)- 36, Euroquol 5 Dimensions (EQ-5D), or the AS specific the ASQuol. These outcome parameters are the basis to conduct clinical trials. The ASessements in AS (ASAS) improvement criteria were developed to evaluate the short term efficacy of Non-Steroidal Antirheumatic Drugs (NSAIDs) and adjusted for the measurement of the high efficacy of the TNF-alpha blocking agents. To examine the x-rays of sacroiliac joints (SIG), the radiological criteria as part of the modified New York criteria are mostly used. For the x-rays of the spine the Bath AS Radiology Index (BASRI) is valuable in daily practice, but the modified Stokes AS Spine Score (mSASSS) is more sensitive for clinical trials. To examine Magnetic Resonance Imag...Continue Reading

References

Jan 1, 1996·British Journal of Rheumatology·S D JonesA Calin
Jan 20, 1998·Arthritis and Rheumatism·J BraunJ Sieper
Dec 14, 2002·Annals of the Rheumatic Diseases·L C DowardM A Chamberlain
Nov 13, 2003·Arthritis and Rheumatism·John C DavisUNKNOWN Enbrel Ankylosing Spondylitis Study Group
Mar 31, 2004·Annals of the Rheumatic Diseases·M C W CreemersP L C M van Riel
Jun 23, 2004·Annals of the Rheumatic Diseases·H HaibelJ Sieper
Dec 21, 2004·Annals of the Rheumatic Diseases·H HaibelJ Sieper
Feb 5, 2005·Arthritis and Rheumatism·Désirée van der HeijdeUNKNOWN Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group
Feb 5, 2005·Arthritis and Rheumatism·Désirée van der HeijdeUNKNOWN ASsessment in Ankylosing Spondylitis International Working Group
May 24, 2005·Zeitschrift für Rheumatologie·C MaurischatM Bullinger
Jun 30, 2005·Arthritis and Rheumatism·Désirée van der HeijdeSjef van der Linden
Jun 1, 2005·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·W GreinerJ-M Graf von der Schulenburg

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Citations

Mar 24, 2010·Zeitschrift für Rheumatologie·T Meyer, H Raspe
Mar 24, 2010·Zeitschrift für Rheumatologie·J Hermann
Sep 28, 2014·Zeitschrift für Rheumatologie·C KamplingJ G Richter
Dec 13, 2007·Rheumatology International·Ernst Feldtkeller, Jon Erlendsson

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