Outcome Prediction of Higher-Risk Brief Resolved Unexplained Events.

Hospital Pediatrics
Amy M DeLarocheJoel Tieder

Abstract

Brief resolved unexplained events (BRUEs) are classified as higher risk on the basis of patient and event characteristics, but there is limited evidence to guide management decisions. The authors of this study aim to describe patients with a higher-risk BRUE, determine the yield of diagnostic evaluation, and explore predictors of clinical outcomes. A retrospective medical record review was conducted for patients ≤365 days of age who were evaluated in a tertiary-care pediatric emergency department with a discharge diagnostic code indicative of a BRUE. Demographic and clinical characteristics, including diagnostic evaluation, are reported. Univariate and multivariate analyses were used to test the association of risk factors with clinical outcomes (serious underlying diagnosis, recurrent events, and return hospitalization). Of 3325 patients, 98 (3%) met BRUE criteria and 88 were classified as higher risk; 0.6% of laboratory and 1.5% of ancillary tests were diagnostic, with 4 patients having a serious underlying diagnosis. Nine patients had recurrent events during hospitalization, and 2 were readmitted for a recurrent BRUE after their index visit. Prematurity was the only characteristic significantly associated with an outcome, in...Continue Reading

References

Mar 11, 2004·The American Journal of Emergency Medicine·Andrew D De PieroJames M Chamberlain
Apr 4, 2007·Pediatrics·Ilene Claudius, Thomas Keens
Apr 16, 2008·The Journal of Pediatrics·Joel S TiederDimitri A Christakis
Oct 28, 2008·The Journal of Pediatrics·Hussein A Al-KindyAurore Côté
Mar 18, 2009·Journal of Child Neurology·Joshua L BonkowskyFrancis M Filloux
Feb 19, 2013·The Journal of Pediatrics·Joel S TiederMichael B H Smith
Jun 14, 2013·Clinical & Developmental Immunology·Elizabeth A MarchantPascal M Lavoie
Sep 11, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tasnee ChonmaitreeRichard B Pyles
Jun 1, 2016·Pediatrics·Joel S TiederUNKNOWN SUBCOMMITTEE ON APPARENT LIFE THREATENING EVENTS
Dec 19, 2017·Expert Review of Molecular Diagnostics·Kerri BasileDominic E Dwyer
Nov 21, 2018·Hospital Pediatrics·Jessica S MeyerMegan Z Cardoso
Aug 12, 2019·Academic Pediatrics·Sriram RamgopalRaymond D Pitetti
Sep 7, 2019·Pediatrics·Sriram RamgopalRaymond D Pitetti

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Citations

Feb 23, 2021·Global Pediatric Health·Rita HaddadAmy M DeLaroche
Mar 14, 2021·Journal of Perinatology : Official Journal of the California Perinatal Association·Grant EricksonCarl E Hunt
Aug 26, 2021·Hospital Pediatrics·Karolina MaksimowskiAmy M DeLaroche
Aug 30, 2021·European Journal of Pediatrics·Sriram RamgopalYiannis Katsogridakis
Jun 30, 2021·Hospital Pediatrics·Amy M DeLarocheUNKNOWN BRIEF RESOLVED UNEXPLAINED EVENTS RESEARCH AND QUALITY IMPROVEMENT COLLABORATIVE

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