Outcome predictors of treatment effectiveness for fungal malignant external otitis: a systematic review

Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
Marta MionA Martini

Abstract

The aim of this review is to summarise literature data on clinical aspects and traditional management of fungal malignant external otitis (FMEO), and to identify potential predictive factors of positive treatment outcome. Articles were initially selected based on their titles or abstracts. Full articles were then retrieved and further scrutinised according to predetermined criteria. Reference lists of selected articles were searched for any missed publications. The selected articles were methodologically evaluated. Of an initial 143 references, 14 were selected that focalised on the management of FMEO. The majority of studies demonstrated a correlation between treatment effectiveness, assessed as symptom resolution, and clinical and management variables: abstention from surgical debridement, absence of facial palsy, Aspergillus spp. as causative pathogen and absence of imaging findings at diagnosis and follow-up. The effectiveness of FMEO treatment depends on the assessment of cranial nerve state, the causative pathogen and imaging findings. Above all, absence of facial nerve palsy, Aspergillus spp. and absence of radiological signs at diagnosis and during follow-up correlate with symptom resolution. The fact that conservative ...Continue Reading

Citations

Mar 9, 2021·Annals of the Royal College of Surgeons of England·W S ChoN Fergie
Jun 9, 2020·The American Journal of Emergency Medicine·Drew A LongBrit Long

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Methods Mentioned

BETA
biopsy

Software Mentioned

SPSS
Scopus
Statistical Package for the Social Sciences ( SPSS

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