Outcome results in children with IgA nephropathy: a single center experience.

International Journal of Nephrology and Renovascular Disease
Ipek Kaplan BulutNida Dincel

Abstract

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis. Patients manifest variable clinical symptoms (eg, microhematuria) with preserved or progressive deterioration of renal function resulting in end-stage renal disease. The aim of this study was to evaluate patients from a single center to describe the clinical features, treatments, and follow-up results of those with the disease. This is a retrospective data study of all children with IgAN. Patients who had a histopathologically proven diagnosis of IgAN and were followed up for at least 5 years were included in the study. Renal biopsy, graded as Hass classification, was performed on all patients. A total of 39 patients were included in the study. The mean follow-up time (± standard deviation) was 10.4 ± 3.51 (range 5-16) years. Twenty-nine patients (74.4%) were male and ten (25.6%) were female. Nineteen (48.7%) patients presented with recurrent macroscopic hematuria, ten (25.6%) with microscopic hematuria ± proteinuria, six (15.4%) with nephritic syndrome, and four (10.3%) with nephrotic syndrome. All patients underwent a renal biopsy, which was graded according to the Hass classification. At the end of follow-up time, 18 (46.1%) patients were norm...Continue Reading

References

Jul 1, 1991·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·T LinnéL Sigström
Nov 3, 1994·The New England Journal of Medicine·J V DonadioK E Holley
Feb 1, 1994·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·R J HoggD A Savino
Dec 1, 1995·The Journal of Pediatrics·R J WyattN A Bishof
Sep 29, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·L P BartosikD C Cattran
May 23, 2003·Journal of the American Society of Nephrology : JASN·Manuel PragaEduardo Hernández
Aug 5, 2003·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Colin C GeddesDaniel C Cattran
Jun 3, 2005·Journal of the American Society of Nephrology : JASN·Jonathan Barratt, John Feehally
Apr 28, 2006·Kidney International·G B Appel, M Waldman
Apr 28, 2006·Kidney International·J Barratt, J Feehally
Jun 3, 2006·Nephron. Clinical Practice·James C M Chan, Howard Trachtman
Jul 11, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kenji WakaiHideto Sakai
Jul 14, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Jaana RonkainenMatti Nuutinen
Jul 11, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ronald J Hogg
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Ronald J HoggUNKNOWN North American IgA Nephropathy Study Group
Jul 3, 2009·Kidney International·UNKNOWN Working Group of the International IgA Nephropathy Network and the Renal Pathology SocietyHong Zhang
Jul 3, 2009·Kidney International·UNKNOWN Working Group of the International IgA Nephropathy Network and the Renal Pathology SocietyHong Zhang

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Citations

May 18, 2016·Nature Reviews. Disease Primers·Kar Neng LaiRichard J Glassock
Mar 22, 2020·Clinical and Experimental Nephrology·Fatma El-Husseiny MoustafaNashwa Hamdy

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Methods Mentioned

BETA
biopsy
urine collected
biopsies

Software Mentioned

SPSS

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