Outcomes According to Discharge Location for Persons Who Inject Drugs Receiving Outpatient Parenteral Antimicrobial Therapy

Open Forum Infectious Diseases
Helen T D'CoutoSandra B Nelson

Abstract

Opioid use disorder poses a significant public health risk. Persons who inject drugs (PWID) suffer from high mortality and morbidity secondary to serious infectious diseases, often requiring prolonged courses of outpatient parenteral antibiotics. The goal of this study was to determine the outcomes of PWID discharged to home or to a skilled nursing or rehabilitation facility (SNF/rehab) with parenteral antibiotic treatment under an outpatient parenteral antimicrobial therapy (OPAT) program. This is a retrospective observational study. The study population was identified via hospital and OPAT databases using substance use disorder diagnoses and confirmed through chart review. The study population included hospitalized PWID with injection drug use in the preceding 2 years who were discharged between 2010 and 2015 to complete at least 2 weeks of parenteral antibiotics and monitored by the OPAT program. Retrospective chart review was used to describe patient characteristics and outcomes. Fifty-two patients met inclusion criteria, 21 of whom were discharged to home and 31 were discharged to a SNF/rehab. Of the patients discharged to home, 17 (81%) completed their planned antibiotic courses without complication. Twenty (64%) patients...Continue Reading

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Citations

Mar 7, 2019·Open Forum Infectious Diseases·Chloe Bryson-CahnShireesha Dhanireddy
Sep 3, 2020·The Journal of Infectious Diseases·Grace E CookseyMichael P Veve
Dec 24, 2019·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·David P Serota, Theresa Vettese
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Aug 13, 2020·Infectious Disease Clinics of North America·Hermione HurleyAlice Thornton
Aug 13, 2020·Infectious Disease Clinics of North America·David P SerotaMarcos C Schechter
Sep 15, 2021·Circulation. Cardiovascular Quality and Outcomes·Raymond Y YeowMatthew C Konerman

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