Outcomes after liver transplantation in accordance with ABO compatibility: A systematic review and meta-analysis

World Journal of Gastroenterology : WJG
Eung Chang LeeSang-Jae Park

Abstract

To evaluate the differences in outcomes between ABO-incompatible (ABO-I) liver transplantation (LT) and ABO-compatible (ABO-C) LT. A systematic review and meta-analysis were performed by searching eligible articles published before No-vember 28, 2016 on MEDLINE (PubMed), EMBASE, and Cochrane databases. The primary endpoints were graft survival, patient survival, and ABO-I-related complications. Twenty-one retrospective observational studies with a total of 8247 patients were included in this meta-analysis. Pooled results of patient survival for ABO-I LT were comparable to those for ABO-C LT. However, ABO-I LT showed a poorer graft survival than ABO-C LT (1-year: OR = 0.66, 95%CI: 0.57-0.76, P < 0.001; 3-year: OR = 0.74, 95% CI 0.64-0.85, P < 0.001; 5-yearr: OR =0.75, 95%CI: 0.66-0.86, P < 0.001). Furthermore, ABO-I LT was associated with more incidences of antibody-mediated rejection (OR = 74.21, 95%CI: 16.32- 337.45, P < 0.001), chronic rejection (OR =2.28, 95%CI: 1.00-5.22, P = 0.05), cytomegalovirus infection (OR = 2.64, 95%CI: 1.63-4.29, P < 0.001), overall biliary complication (OR = 1.52, 95%CI: 1.01-2.28, P = 0.04), and hepatic artery complication (OR = 4.17, 95%CI: 2.26-7.67, P < 0.001) than ABO-C LT. In subgroup analyse...Continue Reading

References

Jan 1, 1992·Transplantation·T H Renard, W S Andrews
Sep 1, 1990·Lancet·J GugenheimH Bismuth
Mar 1, 1990·Acta paediatrica Scandinavica·V P FerrianiI F de Carvalho
Aug 1, 1990·The Journal of Pediatrics·E M SokalP Clapuyt
Sep 1, 1983·Critical Care Medicine·N TaenakaJ Kambayashi
Oct 15, 1995·Transplantation·T V CacciarelliC O Esquivel
Sep 15, 1994·Transplantation·C M LoR W Busuttil
Aug 1, 1993·Journal of Pediatric Surgery·S P DunnK Falkenstein
Aug 1, 1993·Annals of Surgery·L Sanchez-UrdazpalR A Krom
May 1, 1997·The Australian and New Zealand Journal of Surgery·A K ChuiA G Sheil
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Jan 16, 1998·Immunology and Cell Biology·N J WuttkeH Zola
Mar 20, 1999·Transplantation Proceedings·G Varela-FascinettoJ P Vacanti
Jun 5, 2003·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Stanley JordanRobert McEwan
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Jan 8, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Daniel G MalufRobert A Fisher
Feb 10, 2006·JAMA : the Journal of the American Medical Association·Jaime L PetersLesley Rushton
May 25, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Thomas HeffronRene Romero
Jun 15, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mikiko UedaKoichi Tanaka
Dec 13, 2006·Journal of Pediatric Surgery·Yohei YamadaMasaki Kitajima
Feb 23, 2007·Transplant International : Official Journal of the European Society for Organ Transplantation·Takashi SaitoSatoshi Ichiyama
Mar 9, 2007·Transplant International : Official Journal of the European Society for Organ Transplantation·Ilias KoukoutsisSimon R Bramhall
Mar 31, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Hiroto EgawaShinji Uemoto
May 25, 2007·Transplant International : Official Journal of the European Society for Organ Transplantation·Christian TosoNorman M Kneteman
Sep 5, 2007·Molecular Immunology·Martin J GlennieRonald P Taylor
Oct 12, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hiroto EgawaMotohide Shimazu
Jan 12, 2008·Journal of Clinical Apheresis·Lucio UrbaniFranco Filipponi
Jan 6, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A ShakedUNKNOWN A2ALL Study Group
Jun 13, 2009·Pediatric Transplantation·Thomas G HeffronRene Romero
Jul 31, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Zoe A StewartDorry L Segev
Feb 23, 2010·International Journal of Surgery·David MoherUNKNOWN PRISMA Group
Mar 31, 2010·Seminars in Hematology·George J Weiner
Jul 20, 2010·European Journal of Clinical Investigation·Minoru TanabeMasaki Kitajima
Jul 20, 2010·BMJ : British Medical Journal·Eveline NüeschPeter Jüni
Jul 16, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Shao Fa WangXiao Ping Chen

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Citations

Mar 9, 2019·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Surumi ShajahanUma Devi Padma
Jun 7, 2019·Journal of Zhejiang University. Science. B·Ai-Bin ZhangShu-Sen Zheng
Nov 15, 2019·Transplantation Direct·Marcio F Chedid, Emilio Rodrigo
Jul 14, 2020·Frontiers in Immunology·Angus HannM Thamara P R Perera
Jul 10, 2019·Gastroenterology Research and Practice·Dipesh Kumar YadavTingbo Liang

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