Outcomes after surgical treatment of meningioma-associated proptosis

Journal of Neurosurgery
Christian A BowersW T Couldwell

Abstract

OBJECTIVE Meningioma-associated proptosis (MAP) can be cosmetically and functionally debilitating for patients with sphenoorbital and other skull base meningiomas, and there is limited information on the quantitative improvement in proptosis after surgery. Because less extensive removals of tumor involving the orbit fail to reduce proptosis, the senior author has adopted an aggressive surgical approach to the removal of tumor involving the periorbita and orbit. The authors of this study retrospectively reviewed outcomes of this surgical approach. METHODS All surgeries for MAP performed by a single surgeon between January 1, 2002, and May 1, 2015, were reviewed. Age, sex, visual symptoms, number and types of surgical treatments, cavernous sinus involvement, complications, duration of follow-up, residual tumor, use of adjuvant radiation therapy, and extent of proptosis resolution as measured by the exophthalmos index (EI) pre- and postoperatively and at the final follow-up were recorded. RESULTS Thirty-three patients (24 female [73%]) with an average age of 51.6 years were treated for MAP. Of the 22 patients with additional visual symptoms (for example, loss of visual acuity, field cut, or diplopia), 15 had improved vision and 7 ...Continue Reading

References

Jun 1, 1982·Archives of Otolaryngology·D L LarsonR H Jesse
Feb 1, 1994·Journal of Neurosurgery·J C MaroonL Sternau
Oct 31, 2002·Journal of Neurosurgery·Franco DeMonteJames R Patrinely
Mar 1, 1952·Journal of Neurosurgery·F CASTELLANOH OLIVECRONA
May 21, 2009·Ophthalmic Plastic and Reconstructive Surgery·Marcus J HeufelderBernhard Frerich
Dec 28, 2010·Journal of Neurosurgery·Soichi OyaJoung H Lee
Jan 19, 2011·The British Journal of Ophthalmology·Peerooz SaeedMaarten P Mourits

❮ Previous
Next ❯

Citations

Dec 27, 2016·World Neurosurgery·Jacob L FreemanKevin O Lillehei
May 4, 2020·Journal of Neuro-oncology·Justin N Karlin, Howard R Krauss
Oct 20, 2020·Journal of Neurological Surgery. Part B, Skull Base·Amol Raheja, William T Couldwell
Apr 9, 2020·Ophthalmic Plastic and Reconstructive Surgery·Oluwatobi O IdowuM Reza Vagefi
Jun 22, 2021·Frontiers in Oncology·Waseem MasalhaJürgen Grauvogel
Jul 27, 2021·Journal of Neurological Surgery. Part B, Skull Base·Theresa A ElderNicholas Bambakidis
Aug 14, 2021·Journal of Neurosurgery·Alfio SpinaPietro Mortini

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Neurosurgery
J C MaroonL Sternau
Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
Carlos Filipe Chicani, Neil R Miller
Neuro-Chirurgie
T Civit, S Freppel
© 2022 Meta ULC. All rights reserved