Outcomes and clinical characteristics of transmural intestinal necrosis in acute mesenteric ischemia

Scandinavian Journal of Gastroenterology
Xinyu WangWeiwei Ding

Abstract

Background: Acute mesenteric ischemia (AMI) is a rare life-threatening condition, especially for the patients with transmural intestinal necrosis (TIN). However, the optimal time for surgical intervention is controversial. As a series study, this study aimed to identify the outcomes and clinical characteristic of patients with TIN. Methods: Clinical data of 158 patients with AMI from January 2010 to December 2017 were retrospectively analyzed in a national gastrointestinal referral center in China to confirm the outcomes and identify predictors for TIN. Results: According to the results of pathological assessment and follow-up, 62 patients were TIN and 96 were non-TIN. Patients with TIN have a higher mortality and incidence of severe complications. The significant independent predictors for TIN were arterial lactate level (OR: 4.76 [2.29 ∼ 9.89]), free intraperitoneal fluid (OR: 9.49 [2.56 ∼ 35.24]) and pneumatosis intestinalis (OR: 7.08 [1.68 ∼ 29.82]) in computed tomography (CT) scan imaging. The overall area under the receiver operating characteristics (ROC) curve of the model was 0.934 (95% confidence interval: 0.893 ∼ 0.974). Using ROC curve, the cutoff value of arterial lactate level predicting the onset of TIN was 2.65 m...Continue Reading

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Citations

May 7, 2020·AJR. American Journal of Roentgenology·Lorenzo GarzelliMaxime Ronot
Aug 4, 2020·World Journal of Gastroenterology : WJG·Shi-Long SunWei-Wei Ding
Jan 5, 2021·Current Opinion in Critical Care·Annika Reintam BlaserYaseen M Arabi

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