OUTCOMES AND PROGNOSTIC FACTORS ASSOCIATED WITH CANINE SINONASAL TUMORS TREATED WITH CURATIVE INTENT CONE-BASED STEREOTACTIC RADIOSURGERY (1999-2013)

Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Lyndsay KubicekDavid Lurie

Abstract

Stereotactic radiosurgery (SRS) is a relatively new therapeutic option in veterinary oncology. The role of this modality has not been extensively evaluated for the use in canine nasal tumors. The objective of this retrospective, observational study was to describe the clinical outcome and prognostic factors associated with survival times in a sample of canine patients treated with SRS for sinonasal tumors. Fifty-seven dogs with sinonasal tumors met inclusion criteria. Histologic diagnoses included sarcoma (SA) (n = 9), carcinoma (CA) (n = 40), osteosarcoma (OSA) (n = 7), and round cell (n = 1). Four of 57 cases were treated twice with SRS. For these, the median and mean doses delivered were 30Gy and 33Gy, respectively (range 18.75Gy-56Gy). Late effects occurred in 23 cases and ranged from grades I-III. The median overall survival time was 8.5 months. The median overall survival times in dogs with tumor type of CA, SA, and OSA were 10.4, 10.7, and 3.1 months, respectively. Dogs with the tumor type of OSA had shorter overall survival time than that in dogs with tumor type of CA and SA. Findings from this retrospective study indicated that SRS may be beneficial for canine patients with sinonasal tumors, however a controlled clinic...Continue Reading

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Citations

Apr 12, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Zaki JafryValerie J Poirier
Jul 26, 2017·Veterinary and Comparative Oncology·T L Gieger, M W Nolan
Oct 7, 2017·The Veterinary Quarterly·Owen DaviesAna Lara-Garcia
Jul 6, 2018·The Journal of Small Animal Practice·M W Nolan, J M Dobson
Aug 1, 2018·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Elizabeth M DunfieldNeil I Christensen
Jan 19, 2019·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Sonya YuDavid Lurie
Feb 20, 2019·Journal of the American Veterinary Medical Association·Monique N MayerCheryl L Waldner
Jan 22, 2020·Journal of the American Animal Hospital Association·Annie GallowayKeara Boss
Mar 20, 2020·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Stacey Fox-AlvarezLyndsay Kubicek
Apr 14, 2020·Veterinary Ophthalmology·Friederike WolfCarla Rohrer Bley
Jul 24, 2020·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Esther NellJessica Lawrence
Jul 28, 2020·The Journal of Small Animal Practice·J R Mortier, L Blackwood
Jan 19, 2021·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Friederike WolfValeria Meier
Nov 11, 2021·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Ber-In LeeDel Leary

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