Outcomes Are Not Different between Patients with Intermediate and High DWI-ASPECTS after Stent-Retriever Embolectomy for Acute Anterior Circulation Stroke.

AJNR. American Journal of Neuroradiology
Seul Kee KimYun Young Lee

Abstract

Questions remain as to what benefits embolectomy provides to patients presented with considerable early ischemic changes on baseline imaging studies. This study aimed to investigate the impact of the Alberta Stroke Program Early CT Score applied to DWI on treatment outcomes in patients with acute stroke undergoing stent-retriever embolectomy. We retrospectively analyzed the clinical and DWI data from 171 patients with acute anterior circulation stroke who were treated with stent-retriever embolectomy within 6 hours of symptom onset. DWI-ASPECTS scores were analyzed with the full scale or were dichotomized (4-6 versus 7-10). Patients with DWI-ASPECTS ≤3 were excluded from the study. Associations between outcome and clinical and radiologic factors were determined with a multivariate logistic regression analysis. A good outcome was defined as a modified Rankin Scale score of 0-2 at 3 months. The median DWI-ASPECTS was 7 (interquartile range, 6-8). The rates of good outcome, symptomatic hemorrhage, and mortality were not different between high DWI-ASPECTS (scores of 7-10) and intermediate DWI-ASPECTS (scores of 4-6) groups. In patients with an intermediate DWI-ASPECTS, good outcome was achieved in 46.5% (20/43) of patients with suc...Continue Reading

References

Oct 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·P A BarberUNKNOWN ASPECTS Study Group
Mar 1, 2006·NeuroImage·Thanh G PhanDavid C Reutens
Feb 3, 2007·Stroke; a Journal of Cerebral Circulation·Joung-Ho Rha, Jeffrey L Saver
Dec 8, 2007·Stroke; a Journal of Cerebral Circulation·Ken ButcherUNKNOWN EPITHET Investigators
Jun 6, 2009·Stroke; a Journal of Cerebral Circulation·Oliver C SingerUNKNOWN MR Stroke Study Group Investigators
Jul 9, 2010·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Ke LinWalter E Zink
Mar 20, 2012·Stroke; a Journal of Cerebral Circulation·Albert J YooR Gilberto González
Jun 14, 2013·Stroke; a Journal of Cerebral Circulation·Jean-Marc OlivotMikael Mazighi
Aug 8, 2013·Stroke; a Journal of Cerebral Circulation·Osama O ZaidatUNKNOWN STIR Thrombolysis in Cerebral Infarction (TICI) Task Force
Oct 5, 2013·Stroke; a Journal of Cerebral Circulation·Constance de Margerie-MellonCatherine Oppenheim
Mar 7, 2014·Stroke; a Journal of Cerebral Circulation·Sònia AbilleiraUNKNOWN Catalan Stroke Code and Reperfusion Consortium
May 9, 2014·Journal of Neurointerventional Surgery·Seul Kee KimHeoung Keun Kang
May 31, 2014·Stroke; a Journal of Cerebral Circulation·Zhong-Song ShiUNKNOWN Multi MERCI, TREVO, and TREVO 2 Investigators
Dec 18, 2014·The New England Journal of Medicine·Olvert A BerkhemerUNKNOWN MR CLEAN Investigators
Jan 8, 2015·Journal of Neurointerventional Surgery·Italo LinfanteOsama O Zaidat
Feb 12, 2015·The New England Journal of Medicine·Bruce C V CampbellUNKNOWN EXTEND-IA Investigators
Feb 12, 2015·The New England Journal of Medicine·Mayank GoyalUNKNOWN ESCAPE Trial Investigators
Apr 18, 2015·The New England Journal of Medicine·Jeffrey L SaverUNKNOWN SWIFT PRIME Investigators
Apr 18, 2015·The New England Journal of Medicine·Tudor G JovinUNKNOWN REVASCAT Trial Investigators

❮ Previous
Next ❯

Citations

Mar 10, 2017·Topics in Magnetic Resonance Imaging : TMRI·Supada Prakkamakul, Albert J Yoo
Apr 7, 2020·Stroke; a Journal of Cerebral Circulation·Hidehisa NishiSusumu Miyamoto
Aug 12, 2019·Journal of Neurointerventional Surgery·Federico CagnazzoVincent Costalat
Apr 18, 2020·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Jose Danilo B DiestroAditya Bharatha
Nov 12, 2018·Journal of Neurointerventional Surgery·Kevin PhanHamed Asadi
Feb 19, 2021·Reviews in the Neurosciences·Guangchen HeYueqi Zhu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.