Outcomes associated with transfusion in low-risk women with obstetric haemorrhage

Vox Sanguinis
Jillian A PattersonObstetric Transfusion Steering Group

Abstract

Obstetric haemorrhage is associated with increased blood transfusion, morbidity and health service usage in women. While the use of transfusion in actively bleeding patients is supported, there is little evidence for the use of blood as treatment in the nonbleeding patient following obstetric haemorrhage. Transfusion may expose women to increased morbidity. This study aims to compare outcomes between low-risk women receiving no or 1-2 units of blood in the context of obstetric haemorrhage. The study population included women giving birth in hospital in New South Wales, Australia, between July 2006 and December 2010, with a diagnosis of obstetric haemorrhage. Women with medical or obstetric conditions making them high risk were excluded, as were women receiving more than 2 units of blood. Data were obtained from linked hospital, birth and blood bank databases. Propensity score matching was used to compare outcomes between transfused and nontransfused women in order to estimate the impact of the transfusion itself on outcomes. There were 14989 women with obstetric haemorrhage, of whom, 1702 received a transfusion, including 1069 receiving a transfusion of 1-2 units. Women receiving transfusion were more likely to experience sever...Continue Reading

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Citations

Mar 29, 2021·International Journal of Obstetric Anesthesia·D Katz, M K Farber
Apr 22, 2021·International Journal of Epidemiology·Julie M PetersenMatthew P Fox
Nov 19, 2021·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Skandarupan JayaratnamCaroline de Costa

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